A Single Amino Acid Residue Regulates PTEN-Binding and Stability of the Spinal Muscular Atrophy Protein SMN.

Spinal Muscular Atrophy (SMA) is a neuromuscular disease caused by decreased levels of the survival of motoneuron (SMN) protein. Post-translational mechanisms for regulation of its stability are still elusive. Thus, we aimed to identify regulatory phosphorylation sites that modulate function and stability.

Audio-visual interaction in visual motion detection: Synchrony versus Asynchrony.

Objective: Detection and identification of moving targets is of paramount importance in everyday life, even if it is not widely tested in optometric practice, mostly for technical reasons. There are clear indications in the literature that in perception of moving targets, vision and hearing interact, for example in noisy surrounds and in understanding speech. The main aim of visual perception, the ability that optometry aims to optimize, is the identification of objects, from everyday objects to letters, but also the spatial orientation of subjects in natural surrounds.