Publications by authors named "Inga Malecka"
Article Synopsis
- The study aims to compare the demographic, clinical, and laboratory characteristics of multiple sclerosis patients based on their age at diagnosis, as most MS cases occur between ages 20 and 40, an area that lacks extensive research.
- 182 patients were categorized into four age groups (<30, 30-39, 40-49, ≥50), with findings showing an increase in motor symptoms, disease severity, and time to diagnosis as age increased, while the female-to-male ratio remained consistent across groups.
- In laboratory tests, older patients exhibited a lower rate of post-contrast MRI enhancement, indicating potentially different disease characteristics and progression in older age groups with MS.
The aim of this study was to investigate the demographic and clinical characteristics of patients with multiple sclerosis (MS) diagnosed between 1986 and 2015. 333 patients with definite MS were divided into four subgroups according to the following diagnostic criteria: Group A) Poser (n = 145), Group B) McDonald 2000 (n = 66), Group C) McDonald 2005 (n = 62), and Group D) McDonald 2010 (n = 60). We investigated: 1) patient sex and age at diagnosis, 2) symptoms and number of relapses that prompted MS diagnosis, 3) time between first symptoms suggestive of MS and confirmed diagnosis, and 5) Expanded Disability Status Scale (EDSS) score at disease onset.
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