Publications by authors named "Inga Ludwin"

The high efficacy of modern assisted reproductive technology (ART) and increase in the number of noninfertile patients who are using ART for family building in the United States call into question the relevance of the standard, one-size-fits-all infertility evaluation. Here, we explore whether all patients presenting for ART need uterine cavity and tubal assessment and what tests are most appropriate, efficient, and cost-effective in current times.

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Objective: To demonstrate various types of longitudinal vaginal septa (LVS), their classification, and the surgical management of typical and unique morphologic conditions of LVS.

Design: Video presentation of clinical appearance and surgical techniques for treatment of LVS.

Setting: University hospital and two private.

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Objectives: To demonstrate the hymen-sparing management of a blind hemivagina in obstructed hemivagina and ipsilateral renal anomaly (OHVIRA) syndrome with the use of transrectal ultrasound (TRUS)-guided vaginoscopic septoplasty supported by pre- and postoperative diagnostics with the use of a novel ultrasound technique: 3-dimensional saline-solution infusion contrast sonovaginocervicography (3D-SVC) with virtual speculoscopy.

Design: Video presentation of surgical and ultrasound techniques.

Setting: University hospital and two private centers.

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Objectives: To demonstrate a minimally invasive approach and management in three different types of Robert's uterus.

Design: Video presentation of surgical and ultrasound techniques.

Setting: University hospital and two private centers.

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Objectives: The "Y sign" at the level of the 3-vessel and trachea view corresponds to thinning of main pulmonary artery and arterial duct and a dilated transverse aortic arch. The purpose of this study was to evaluate the Y sign for the diagnosis of aortic dextroposition anomalies at the time of the first-trimester scan and to assess the screening performance of only the Y sign, only abnormal left axis deviation (axis sign), and their combination for the diagnosis of aortic dextroposition anomalies.

Methods: A prospective evaluation of 6025 pregnant women undergoing first-trimester ultrasonography was conducted.

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Purpose:  To estimate the inter-observer reliability and agreement of offline analyses of three different ultrasound techniques for assessing tubal patency.

Methods:  100 tubes (n = 100) in 50 women were evaluated for tubal patency between November 2013 and July 2015 using ultrasound as index tests and laparoscopy as the reference standard. Three different ultrasound techniques were applied: two-dimensional grayscale ultrasound using air + saline as the contrast media (2D-HyCoSy); two- and three-dimensional grayscale ultrasound using foam as the contrast media (2 D/3D-HyFoSy); and the same technique but adding bi-directional power Doppler (2 D/3D-Doppler-HyFoSy).

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Study Objective: To determine the pain intensity and incidence of mild to severe pain during the ultrasound assessment of the uterine cavity and tubal patency using saline, air and saline, and foam as contrasts with and without painkiller.

Design: Prospective observational study (Canadian Task Force classification II-1).

Setting: Private clinic.

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Introduction: Abnormal uterine bleeding (AUB) is the most common symptom of endometrial cancer (EC) and endometrial hyperplasia with (AH) or without (EH) atypia. Risk of malignancy and hyperplasia is significantly lower in premenopausal than in postmenopausal women. Only 10% of EC occurs before menopause.

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Objective: The aim of the study was to compare the natural menopause ages of healthy women with those of women with methotrexate (MTX)-treated rheumatoid arthritis (RA), and to specifically assess the effect of disease onset and activity and the use of MTX on the age of the last menstruation.

Methods: We performed a retrospective review of medical records to identify the ages at which menopause occurred in women with premenopausal RA treated with MTX and in women with postmenopausal onset, irrespective of therapy. Natural menopause ages were also compared between participants with and without RA.

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Article Synopsis
  • - The study aimed to compare the effectiveness of a combined screening test and an ultrasound-based method for detecting trisomy 18 (T18) in pregnant women, particularly looking at different cutoffs and age factors.
  • - Conducted with over 10,800 pregnancies, the findings showed that the ultrasound method had a 100% detection rate for T18, while the combined screening method had an 86% detection rate at a 3% false-positive rate.
  • - The results indicated that the ultrasound screening was more consistent across various maternal age groups, making it a preferable option over the combined screening method for T18 detection.
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Objectives: To identify the most common first-trimester ultrasound findings in Turner syndrome (TS). To evaluate which first-trimester findings can be best used to predict the likelihood of TS.

Methods: This was a prospective study, based on singleton pregnancies.

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Objective: To estimate the inter-rater/intrarater reliability of the European Society of Human Reproduction and Embryology/European Society for Gynaecological Endoscopy (ESHRE-ESGE) classification of congenital uterine malformations and to compare the results obtained with the reliability of the American Society for Reproductive Medicine (ASRM) classification supplemented with additional morphometric criteria.

Design: Reliability/agreement study.

Setting: Private clinic.

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Introduction: Human papillomavirus (HPV) is the most common sexually transmitted infection. Data reporting vertical transmission of HPV from the mother to the fetus are inconsistent and scant. Vertical transmission may occur by hematogenic route (transplacental), or by ascending contamination, or through the birth canal, which may result in the dreaded and rare laryngeal papillomatosis.

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Objective: To compare the diagnostic accuracy of three-dimensional sonohysterography (3D-SIS) and office hysteroscopy in uterine cavity assessment after hysteroscopic metroplasty (HM) and determine the interrater/intrarater agreement for 3D-SIS.

Design: Prospective observational study.

Setting: University hospital, private hospital, and clinic.

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Study Objective: To predict the 1-step complete resection rate after transrectal ultrasound-guided hysteroscopic myomectomy and to determine the usefulness of intraoperative transrectal ultrasonography (TRUS) in monitoring hysteroscopic electroresection of submucosal myomas.

Design: Prospective cohort study (Canadian Task Force classification II-1).

Setting: University hospital.

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Objectives: Premature ovarian failure (POF) is a consequence of gonadotoxic chemoradiotherapy given in antyneoplasia treatment. In young women it will correlate with menopausal symptoms which tend to appear due to depleted ovarian follicle reserve.

Design: It was a case series study that included women 18-50 years old who were treated for malignancy with gonadotoxic chemioradiotherapy.

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Study Objective: To estimate the diagnostic accuracy and to compare the diagnostic value of 3-dimensional sonohysterography (3D-SIS), 3-dimensional transvaginal ultrasonography (3D-TVS), 2-dimensional sonohysterography (2D-SIS), and 2-dimensional transvaginal ultrasonography (2D-TVS) (initial and expert diagnosis) in the differential diagnosis of septate, bicornuate, and arcuate uteri.

Design: Prospective clinical study (Canadian Task Force II-2).

Setting: University hospital and private hospital and clinic.

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Article Synopsis
  • - Cytostatic drugs extravasation is a serious complication that can occur during chemotherapy, potentially threatening health and diminishing the quality of life for cancer patients.
  • - Effective prevention, quick detection, and proper treatment can significantly minimize the negative effects of extravasation.
  • - Training for healthcare professionals and educating patients are crucial in managing and preventing complications related to drug extravasation.
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Aim: to assess the incidence of HPV -DNA in women with ASC/AGC compared to patients with normal Pap smears.

Material And Methods: The study group consisted of 242 women (207 ASC and 35 AGC cases). The control group counted 200 age-matched women with negative Pap smears.

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Aim: To evaluate the diagnostic accuracy of sonohysterography (SHG), hysterosalpingography (HSG) and diagnostic hysteroscopy (DH) in uterine anomaly detection and to assess the role of these various modalities in the differential diagnosis of arcuate, septate and bicornuate uteri.

Methods: Eighty-three women, with a history of recurrent spontaneous abortions or infertility and initial diagnosis of uterine anomaly were included in the study. Diagnostic work-up comprised of SHG, HSG and DH.

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Aim Of The Study: the evaluation of influence of abnormal vaginal biocoenosis on presence and maintenance ASC and AGC in Pap smears.

Methods: The study group consisted of 242 non-pregnant women (25-65 years of age): 207 women (4.96%) with atypical sqamous cells and 35 (0.

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