The study investigates how prior social disruption stress and group testing affect writhing behavior caused by acetic acid-induced visceral pain in mice.
Mice exposed to social disruption exhibited more writhing compared to those not exposed, but testing in groups reduced writhing compared to individual tests.
Findings suggest that the increased pain response due to stress may involve higher TRPV1 receptor levels, while group testing reduces pain sensitivity possibly by influencing brain function in the medial septum.