J Antimicrob Chemother
August 2014
J Antimicrob Chemother
November 2013
Objectives: This study was designed to verify the cytotoxic activity of S-nitrosoglutathione (GSNO) against intracellular Leishmania amastigotes and to test its efficacy as a topical treatment of localized cutaneous leishmaniasis (LCL) in Leishmania major- or Leishmania braziliensis-infected mice.
Methods: Cytotoxic activity of GSNO was verified in L. major-infected THP-1 macrophages.