Publications by authors named "Ineta Grisle"
Article Synopsis
- Vaccination is essential for controlling COVID-19, but hesitancy is a challenge, especially among patients with severe asthma; this study explores their vaccination experiences.
- A questionnaire was distributed to patients with severe asthma across 12 European countries, revealing that 88% of participants had been or planned to be vaccinated, while 9.5% hesitated and 3% refused; beliefs about vaccines influenced these decisions.
- Most patients reported mild or no side effects and noted minimal impact on asthma symptoms post-vaccination, with nearly all vaccinated individuals recommending the vaccine to others in their situation.
Article Synopsis
- The study focused on real-life patients with severe asthma starting anti-interleukin-5 (IL5) treatment in Europe, assessing how they differ from those included in randomized controlled trials (RCTs).
- Out of 1231 patients, only about 27% met the eligibility criteria of RCTs, with key differences in smoking history, clinical factors, and medication use noted.
- The findings highlight that many patients who could benefit from anti-IL5 therapies may be overlooked in clinical trials, underscoring the value of studying broader patient populations in real-world settings.
Introduction: Treatment with biologics for severe asthma is informed by international and national guidelines and defined by national regulating bodies, but how these drugs are used in real-life is unknown.
Materials And Methods: The European Respiratory Society (ERS) SHARP Clinical Research Collaboration conducted a three-step survey collecting information on asthma biologics use in Europe. Five geographically distant countries defined the survey questions, focusing on seven end-points: biologics availability and financial issues, prescription and administration modalities, inclusion criteria, continuation criteria, switching biologics, combining biologics and evaluation of corticosteroid toxicity.
Article Synopsis
- - The COVID-19 pandemic prompted healthcare providers in Europe to adapt severe asthma care, with significant shifts towards video/phone consultations and home-administered biologics.
- - A study surveyed 1101 patients and 268 physicians, revealing that 79% of patients were satisfied with remote consultations, while 62% were satisfied with home-administered biologics.
- - Many physicians anticipate these changes will persist post-pandemic, although the long-term satisfaction of patients may vary as care evolves.