Rituximab associated neutropenia: description of three cases and an insight into the underlying pathogenesis.

Background: To describe Rituximab associated neutropenia (RAN), and to explore its underlying mechanism.

Case Report: We describe three patients with RAN. The effect of patient's plasma on colony forming unit, Granulocyte-Monocyte (CFU-GM) was measured by the addition of plasma to the culture of a healthy bone-marrow.