Is Tumor Budding a New Predictor for Early Cystectomy in pT1 High-Grade Bladder Cancer?

Unlabelled: Background & Objectives: We aimed to evaluate the risk of progression in high-grade T1 (HGT1) tumors using tumor budding (TB) and other standard clinical and histological features. TB is defined as an isolated cancer cell or a cluster composed of fewer than 5 cells scattered in the stroma and is usually used as a strong predictor of lymph node metastasis in T1 colorectal cancer.

Methods: This is an observational longitudinal cohort study involving 168 consecutive patients with HGT1 between 2013 and 2016.

[Embolizing cardiac hibernoma and acute respiratory failure].

Not only ae cardiac hibernomas rare, ante-mortem diagnosis is poor, due to the clinical and radiological similarity with other intracardiac masses. Furthermore, cardiac hibernomas can be asymptomatic and thus escape detection with imaging studies. We present a case of an 81-year-old woman who died as a result of pulmonary tumor embolism.

Colonic necrosis due to calcium polystyrene sulfonate (Kalimate) not suspended in sorbitol.

Cation-exchange resins are used in the management of hyperkalemia, particularly in patients with end-stage renal disease. These resins were associated with gastrointestinal tract lesions, especially sodium polystyrene sulfonate (Kayexalate) mixed with sorbitol. We present a case of colonic necrosis after the administration of calcium polystyrene sulfonate (Kalimate) not suspended in sorbitol.

[Priapism secondary to penis infiltration of bladder cancer].

Metastasic priapism is a rare entity produced by tumor cell implantation or direct infiltration of corpora cavernousum of the penis. In up to 80% of cases the primary tumor has an urological origen like prostate or bladder cancers. Treatment depends on syntomatology and patient's prognosis.

[Late pathology advances in the diagnosis and prognosis of prostate cancer].

This review article presents the late advances in the pathologic diagnosis of prostate cancer, new concepts and predictive factors, emphasizing the new biomolecular markers in prostate cancer.