S-100 Negative Granular Cell Tumor of the Oral Cavity.

Classic granular cell tumor is a mesenchymal neoplasm that commonly occurs on the skin, but is not infrequently found in the oral cavity, primarily on the dorsal tongue. Diagnosis is usually straightforward with hematoxylin and eosin stained slides. Immunohistochemical studies on classic granular cell tumor shows positive immunostaining for S-100 and vimentin, while CD68 is variably positive.

Management of the anxious dental patient.

The anxious patient in the dental office reacts with panic and inability to cooperate with necessary treatment. It is the dentist's responsibility to recognize and assuage the patient's anxiety on both psychological and medical levels. The diagnosis, etiology and treatment of anxiety will be investigated and presented as any other disease entity.

Ghost cell odontogenic tumor associated with odontoma--report of two rare cases.

The ghost cell odontogenic tumor (GCOT) is a neoplastic/cystic lesion with a diverse histopathological and clinical behavior It was formerly known as calcified odontogenic cyst, but in 2005 the World Health Organization categorized this lesion as an odontogenic, benign tumor rather than a cyst; nominating this neoplasm as calcifying cystic odontogenic tumor. A later comprehensive classification named it ghost cell odontogenic tumor because the most remarkable histopathologic characteristic is the presence of a mass of ghost cells embedded in the epithelium. We report two cases of a rare variant of a ghost cell odontogenic tumor associated with odontoma; to our knowledge, one is the youngest patient (four month old) reported in the English literature.

Submandibular gland MALT lymphoma associated with Sjögren's syndrome: case report.

Lymphoma is a common disease of the head and neck. Mucosal-associated lymphoid tissue (MALT) lymphoma constitutes a rare type of extranodal lymphoma. The Waldeyer's ring is one of the most common sites of occurrence, but MALT lymphoma may also arise in salivary glands, lung, stomach, or lacrimal glands.

Clinical variant of ablepharon macrostomia syndrome.

Ablepharon syndrome is an extremely rare genetic problem that causes severe craniofacial deformities and numerous other abnormalities of the face, genitalia, and skin. The literature regarding this condition is scarce. We present a case of this syndrome with dental manifestations, not reported before, and discuss its characteristics in order to increase the knowledge of this condition among the dental profession.

Brown tumor as a result of hyperparathyroidism in an end-stage renal disease patient.

A 49-year-old male with known history of end-stage renal disease (ESRD) presents with an intraoral exophytic mass of the right mandible. This lesion was given a histologic diagnosis of a Brown tumor. Purpose.

Primary maxillofacial large B-cell lymphoma in immunocompetent patients: report of 5 cases.

Lymphomas of the oral cavity represent 5% of all lymphomas. They usually occur in immunocompromised patients. Lymphoma arising within a single bone, without visceral or lymph node involvement, is known as primary intraosseous lymphoma.

A holistic approach to a rare pathology.

A case of cystic hygroma (CH), a congenital lymph-filled multicystic hamartoma of the neck, with a holistic approach to patient management is presented. The stigma of the CH imposed by attending physicians, dentists, parents, teachers and peers affected the psychological development of this patient since her diagnosis in childhood. Although surgery relieves the threat of airway obstruction and may improve the esthetic appearance of the CH, the patient may be isolated and traumatized by the ignorance and superstitions of the individuals she encounters on a daily basis.

Pigmentary demarcation lines (Futcher lines): an orofacial case.

Pigmentary demarcation lines are rare physiologic pigmentations shaped as lines of deeper discoloration with abrupt transition from less pigmented areas. These lines are known and seen by dermatologists in the skin of African, Indian, and Japanese patients, usually females. No report of intraoral pigmentary demarcation lines was found in the literature.

Cryopreserved amniotic membrane for modulation of periodontal soft tissue healing: a pilot study.

Background: The purpose of this randomized study is to evaluate cryopreserved amniotic membrane (CAM) for helping cicatrization and wound healing after dental implant surgery. Epithelialization, pain, infection, inflammation, and scarring were studied.

Methods: CAM was placed in surgical wounds related to implant surgery.

Toxic epidermal necrolysis. A case report.

We present an extreme case of Toxic Epidermal Necrolysis, which corresponds to a severe form of Stevens Johnson Syndrome. This is a potentially fatal immune reaction that affects skin and mucosa, producing blisters and sloughing of the epithelium. Severe sequelae, including blindness, hearing loss, tooth malformation and esophageal destruction are seen in this case.

Conservative treatment of a pathologic fracture in a patient with Gorham-Stout disease.

Gorham-Stout disease, or massive osteolysis, is an extremely rare idiopathic condition characterized by spontaneous, localized relentless resorption of one or several contiguous bones. There is no known successful treatment. Autologous bone graft also resorbs.

Hereditary osteodystrophy with multiple hormone resistance--a case report.

Hereditary Osteodystrophy, also called pseudohypoparathyroidism, Type 1A (PHP), is a very rare condition composed of a heterogeneous group of autosomal dominant disorders with the common feature of organ resistance to multiple hormones. These patients produce the right amount of hormones but there is resistance to its effect. PHP is difficult to diagnose and the lack of diagnosis may have serious implications for the patient.

Odontogenic carcinoma differentiation into rhabdomyosarcoma: report of a rare case.

To the authors' knowledge, this is the first reported case of an odontogenic carcinoma with documented skeletal muscle differentiation (rhabdomyosarcoma). The histology and clinical features of this aggressive odontogenic neoplasm are described. Within the English-language literature, only 2 cases are reported of an odontogenic tumor with muscle differentiation: a benign odontogenic tumor (ameloblastoma) with differentiation into a rhabdomyosarcoma and an odontogenic sarcoma with smooth-muscle differentiation.

Central mucoepidermoid carcinoma with an atypical radiographic appearance.

Central mucoepidermoid carcinoma (CMC) is a rare osseous neoplasm occurring most often in the fourth to seventh decades of life. Its usual presentation is one of a locally destructive radiolucent lesion found primarily in the mandible, in the premolar region. No reported case to date has shown a mixed radiolucent-radiopaque expression of this tumor.

Osteoid osteoma of the zygoma: report of an unusual case.

Background: Osteoid osteoma is a benign tumor of bone characterized by pain, usually occurring at night, that shows a dramatic response to aspirin. The literature contains reports of only a few cases in the head and neck region.

Case Description: The authors present an unusual case of an osteoid osteoma of the craniofacial bones.

Alport syndrome. Report of a case with severe maxillofacial manifestations.

Alport syndrome (AS) represents a genetic cause of renal failure that affects about 1 in 5,000 Americans. In cases of AS, the problem resides on the X chromosome. Specific mutations to the gene cause defects in one of several subunits of Type IV collagen.

Central ossifying fibroma: an analysis of 20 cases and review of the literature.

Central ossifying fibroma is the most common benign fibro-osseous neoplasm of the jaw. It is not easy to diagnose ossifying fibroma because its clinical, radiographic, and histologic criteria often overlaps with other fibro-osseous lesions. Based on the analysis of 20 cases, this article describes all the manifestations of central ossifying fibroma and some of the differences with the so-called juvenile active ossifying fibroma.

Cystic hygroma.

Cystic hygroma (CH) is a benign, developmental condition of unknown etiology. 90% of the cases are present by age 2. CH represents malformed lymphatics that fail to communicate with larger veins and, therefore, they collect lymph.