The occurrence and resistance of Shigella flexneri CECT4804 to acid stress in vitro and in vivo.

The ability to maintain intra‑cellular pH is crucial for many microbes mainly the enterobacteria to survive in diverse environments, particularly those that undergo fluctuations in pH. In this context, the growth and survival of Shigella flexneri at different acid pH values were evaluated to explain the response strategies involved in the adaptation of S. flexneri CECT4804 in acid stress conditions.