Publications by authors named "Ines Sampaio"
The heterogeneity of psychiatric disorders makes researching disorder-specific neurobiological markers an ill-posed problem. Here, we face the need for disease stratification models by presenting a generalizable multivariate normative modelling framework for characterizing brain morphology, applied to bipolar disorder (BD). We employed deep autoencoders in an anomaly detection framework, combined with a confounder removal step integrating training and external validation.
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- Immune-checkpoint inhibitors (ICI) are monoclonal antibodies that boost the body's antitumor response but can lead to side effects, notably thyroid dysfunction and hypophysitis.
- A retrospective study at an oncologic center analyzed 161 patients treated with ICIs from 2014 to 2019, revealing that 18% developed new thyroid function test abnormalities, with various types reported.
- Patients with thyroid dysfunction showed significantly better overall response rates and survival compared to those without, suggesting that these thyroid issues might be indicative of improved ICI treatment outcomes.
Background: Few studies in Portugal have attempted to assess the impact of psychological interventions in primary health care regarding the problems shared by clients, and which variables predicted the success of this intervention. The current study, therefore, aimed to identify predictors of success related to psychological intervention in a single primary health care center in the north of Portugal.
Method: This was a retrospective study from secondary data, using the data from 1024 clients who attended the psychological consultation at a primary health care center over a period of 8 years.
Objective: Metastatic disease is common in medullary thyroid carcinoma (MTC) and it is usually detected by raising calcitonin and carcinoembryonic antigen (CEA) levels. Nuclear medicine imaging has an important role in lesion identification/characterisation. We aim to compare Ga-DOTANOC PET/CT and F-FDG PET/CT performance and to explore the correlations between tumoral markers and functional imaging.
View Article and Find Full Text PDFIntroduction: The purpose of this article is to report the experience of the Portuguese Institute of Oncology - Porto in the treatment of gastroenteropancreatic neuroendocrine tumors with 177Lu-DOTA-TATE, regarding the safety and efficacy of this treatment modality.
Material And Methods: A retrospective analysis of clinical reports of patients with gastroenteropancreatic neuroendocrine tumors undergoing treatment with 177Lu-DOTA-TATE between April 2011 and November 2013 was performed.
Results: Thirty six cases were reviewed and 30 completed all 3 cycles of 177Lu-DOTA-TATE (83.