Publications by authors named "Ines Saenz de Miera"
Article Synopsis
- * Among patients with pseudomembranes, fever was significantly more common, suggesting a possible link, but no differences were noted in the use of immunosuppressant drugs or overall clinical outcomes.
- * The research concludes that even though pseudomembranes are rare in hospitalized IBD patients with CDAD, their presence does not affect the severity of clinical outcomes or hospitalization duration.
Background & Aims: Management of Clostridium difficile infection in patients with flaring inflammatory bowel disease (IBD) has not been optimized. We investigated the effects of combination therapy with antibiotics and immunomodulators in patients with IBD and C difficile infection.
Methods: We analyzed data from 155 patients (59% with ulcerative colitis [UC]) from a retrospective, European Crohn's and Colitis organization, multi-center study comparing outcome of hospitalized IBD patients with C difficile infection who were treated with antibiotics (n = 51) or antibiotics and immunomodulators (n = 104).