Publications by authors named "Ines Romo-Palafox"
Genetic Polymorphisms in SOD (rs2070424, rs7880) and CAT (rs7943316, rs1001179) Enzymes Are Associated with Increased Body Fat Percentage and Visceral Fat in an Obese Population from Central Mexico.
César Hernández-Guerrero Paulina Hernández-Chávez Inés Romo-Palafox Grecia Blanco-Melo Alicia Parra-Carriedo
Arch Med Res
July 2016
Article Synopsis
- Oxidative stress is linked to obesity-related issues, and specific genetic variations (SNPs) in antioxidant enzymes like SOD1 and CAT may influence obesity-related health outcomes.
- A study involving 416 Mexican women found that those with obesity had significantly higher rates of the SOD1 -251A>G genetic variant compared to normal-weight individuals.
- The presence of certain genetic mutations was associated with increased body fat, visceral fat, and higher blood pressure in obese participants, suggesting a connection between these SNPs and obesity severity.
Prevalence of metilentetrahidrofolate reductase C677T polymorphism, consumption of vitamins B6, B9, B12 and determination of lipidic hydroperoxides in obese and normal weight Mexican population.
César Hernández-Guerrero Inés Romo-Palafox Mary Carmen Díaz-Gutiérrez Mariana Iturbe-García Alejandra Texcahua-Salazar
Nutr Hosp
November 2013
Article Synopsis
- Oxidative stress contributes to obesity-related health issues, and the MTHFR enzyme, influenced by its C677T genetic variant, may play a role in this process by affecting folate metabolism and homocysteine levels.
- The study aimed to assess the frequency of the C677T SNP in the MTHFR gene, evaluate the intake of vitamins B6, B9, and B12, and measure lipid hydroperoxide levels in obese and non-obese individuals.
- Findings indicated no significant difference in the C677T variation or vitamin consumption between normal-weight and obese groups, but there was a notable increase in lipid hydroperoxide levels in the obese group, highlighting oxidative stress across obesity levels.
Objective: To compare the production of pro- and anti-inflammatory cytokines by whole blood samples stimulated with lipopolysaccharide from normotensive and preeclamptic women.
Methods: The synthesis of tumor necrosis factor-α, interleukyn-1β, interleukin-6 and interleukin-10 were assayed by immunosorbent assays in 56 and 50 preeclamptic and normotensive women, respectively.
Results: Preeclamptic women showed a higher synthesis (p < 0.