Natural history of nonfunctioning pituitary adenomas and incidentalomas: a systematic review and metaanalysis.

Context: The natural history of pituitary incidentalomas (PIs) and nonfunctioning pituitary adenomas (NFPAs) remains poorly understood.

Objective: The objective of the study was to synthesize the literature on the prognostic factors involved in the progression of PIs and NFPAs in patients followed up conservatively.

Data Sources: We searched MEDLINE, EMBASE, and Cochrane CENTRAL.

Outcomes of surgical treatment for nonfunctioning pituitary adenomas: a systematic review and meta-analysis.

Background: Surgery is commonly used in the management of pituitary nonfunctioning adenomas (NFPA). The goal of this systematic review and meta-analysis is to evaluate the effect of surgery on mortality, surgical complications, pituitary function and vision.

Methods: We searched MEDLINE, EMBASE and Cochrane CENTRAL, queried experts and reviewed the reference list of included publications.