Evans syndrome (ES) is a rare and chronic autoimmune disease characterized by the concomitant or sequential association of auto-immune hemolytic anemia (AIHA) with immune thrombocytopenia (ITP), and less frequently autoimmune neutropenia. Coronavirus disease 2019 (Covid-19) may cause various hematologic conditions. COVID-19 may also induce Evans syndrome via immune mechanisms.
View Article and Find Full Text PDFIntroduction: Hematological disorders are the third cause of hypereosinophilia, after allergic and parasitic disease. The objective of our study is to show the epidemiological, clinical, biological and therapeutic characteristics of hematological hypereosinophilia.
Patients And Methods: This is a retrospective study over a 4-year period (March 2017-March 2021) concerning 14 patients with hematological hypereosinophilia.
Unlabelled: Acquired von Willebrand syndrome is a rare bleeding disorder with laboratory findings similar to those of inherited von Willebrand disease. Principal factors distinguishing acquired von Willebrand syndrome from the latter condition include lack of prior bleeding disorders, diagnosis at older age, negative family history and association with underlying conditions.
Methods: Retrospective, monocentric descriptive case series of acquired von Willebrand syndrome diagnosed between 2010 and 2020.
Le syndrome de Willebrand acquis (SWa) est un syndrome hémorragique rare dont la fréquence est probablement sous-estimée. Les signes cliniques et le bilan d'hémostase sont comparables à ceux de la maladie de Willebrand héréditaire, mais les patients atteints du SWa n'ont pas d'antécédents hémorragiques, personnels ou familiaux. Il s'agit le plus souvent de personnes âgées et ce sont les saignements cutanéomuqueux qui sont les plus fréquents.
View Article and Find Full Text PDFMyelodysplastic syndromes (MDS) are myeloid disorders with various clinical and biological presentations. The French-American-British (FAB-1982) classification included five categories basing on morphology and bone marrow blast count. Three criteria are taken into account: 1) the percentage of blasts in peripheral blood and bone marrow, 2) the percentage of ringed sideroblasts, and 3) the number of monocytes in peripheral blood.
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