[Monitoring medication errors in an internal medicine service].

Background: Patients admitted to internal medicine services receive multiple drugs and thus are at risk of medication errors.

Aim: To determine the frequency of medication errors (ME) among patients admitted to an internal medicine service of a high complexity hospital.

Material And Methods: A prospective observational study conducted in 225 patients admitted to an internal medicine service.

The economic impact of introducing serotonin-noradrenaline reuptake inhibitors into the Brazilian national drug formulary: cost-effectiveness and budget-impact analyses.

Objective: To determine the cost effectiveness, from the Brazilian Ministry of Health viewpoint, of three antidepressant classes for major depressive disorder (MDD), and the budget impact of introducing serotonin-noradrenaline (norepinephrine) reuptake inhibitors (SNRIs) into the current Brazilian national drug formulary, assuming a 6-month treatment duration.

Methods: An existing decision-tree model was adapted to Brazil, based on local guidelines. Clinical data were obtained from published meta-analyses.