Publications by authors named "Ineke M J Pruijn"
Article Synopsis
- - The text discusses how symptoms of acute upper airway obstruction and dysphagia can suggest serious conditions like laryngeal cancer, but it also highlights a rare condition called diffuse idiopathic skeletal hyperostosis (DISH) that can mimic these symptoms.
- - The case study includes two elderly males who experienced serious swallowing issues and airway obstructions due to large bone growths (osteophytes) in their neck areas.
- - The conclusion emphasizes the need for healthcare providers to consider DISH when diagnosing similar symptoms, as early identification can lead to effective treatment and improved patient outcomes, avoiding more drastic interventions.
Objective: To assess the effect of wait and scan (W&S) and stereotactic radiosurgery (SRS) on health-related quality of life (HRQoL) over time in patients with a stable vestibular schwannoma (VS) and growing VS.
Study Design: Longitudinal, multicenter, observational study.
Setting: Tertiary expert center for VS (Radboudumc Nijmegen) and Gamma-Knife center ETZ Hospital Tilburg.
Purpose: During counseling and management of patients with vestibular schwannoma (VS), the emphasis is shifting from tumour control and nerve preservation towards maintaining or improving health-related quality of life (HRQoL). Understanding the patients' perspective and impact of VS is, therefore, of utmost importance. The current study aimed to identify treatment outcomes preferred by patients and to explore the patient-reported VS symptoms and management-related side effects and their impact on HRQoL.
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- The study investigates the validity of subclassifying Koos 2 vestibular schwannoma (VS) tumors based on their size and proximity to the brainstem, challenging the standard practice of immediate treatment following growth detection.
- Six experts evaluated 43 MRI scans to assess the reliability of the classification, finding a near-perfect agreement on Koos 2a tumors and high agreement on Koos 2b tumors.
- Results showed excellent reliability among raters, suggesting that this refined classification can help inform treatment decisions that prioritize patient-centered care rather than just tumor size growth.
Aim: To compare the effect of bilateral submandibular duct ligation and botulinum neurotoxin A (BoNT-A) on drooling severity and its impact on daily life and care in children and adolescents with moderate-to-severe drooling.
Method: This was a randomized, interventional, controlled trial in which 53 children and adolescents (31 males, 22 females, mean age 11y, range 8-22y, SD 2y 10mo) with cerebral palsy (58.5%) or other non-progressive developmental disorders (41.
Objectives: Patients with a vestibular schwannoma (VS) experience a reduced quality of life (QoL). The main objective of this study was to determine the strongest predictors reducing physical and mental QoL from the disease-specific Penn Acoustic Neuroma Quality of Life (PANQOL) questionnaire in patients with VS.
Design: Observational study.
We report a case of a patient with concurrent myotonic dystrophy and recurrent pleomorphic adenoma and hypothesize the association between both diseases. A 58-year-old man with classic myotonic dystrophy type 1 was diagnosed with pleomorphic adenoma. Appropriate treatment was commenced.
View Article and Find Full Text PDFAim: To assess: (1) the effect on drooling of bilateral submandibular duct ligation as surgical therapy after the administration of submandibular botulinum neurotoxin A (BoNT-A) for excessive drooling and (2) the predictive value of treatment success with BoNT-A on treatment success after bilateral submandibular duct ligation.
Method: This was a within-participant retrospective observational study in which 29 children with severe drooling (15 males, 14 females) received BoNT-A treatment at a mean age of 9 years 6 months (SD 2y 5mo), followed by bilateral submandibular duct ligation at a mean age of 10 years 11 months (SD 2y 4mo). Fifteen children were diagnosed with cerebral palsy (CP), with 12 children classified in Gross Motor Function Classification System levels IV and V.