Publications by authors named "Ine Claes"
Cystic Fibrosis (CF) is a life-long genetic disease, causing increased energy needs and a healthy diet with a specific nutrient distribution. Nutritional status is an indicator of disease prognosis and survival. This study aimed at assessing the effectiveness of a self-management mobile app in supporting patients with CF to achieve the dietary goals set by the CF nutrition guidelines.
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- Patients with cystic fibrosis (CF) often require Pancreatic Enzyme Replacement Therapy (PERT) to digest dietary fats, but determining the right dose for each meal can be difficult.
- This study tested a mobile app that supports PERT dosing based on individual food types and in vitro digestion research, with patients tracking their diet and enzyme use over a month.
- Results showed that while overall fat absorption remained stable, the app helped narrow the range of PERT doses needed, and children with initially low fat absorption saw significant improvements after following the app's dosing recommendations.
Background: Most patients with cystic fibrosis (CF) suffer from pancreatic insufficiency, leading to fat malabsorption, malnutrition and abdominal discomfort. Until recently, no specific tool was available for assessing gastro-intestinal related quality of life (GI QOL) in patients with CF. As the Horizon2020 project MyCyFAPP aims to improve GI QOL by using a newly designed mobile application, a sensitive and reliable outcome measure was needed.
View Article and Find Full Text PDFBackground: Optimal nutrition for children with cystic fibrosis (CF) improves prognosis and survival, but an increased caloric intake recommendation for this population raises concerns about the nutrient profile of their diets.
Objective: Our aim was to assess the relative contribution of food groups to the total macronutrient intake of European pediatric patients with CF.
Design: We conducted a cross-sectional study in which the participants recorded dietary intake from 2016 to 2017.
Background: A method to adjust Pancreatic Enzyme Replacement Therapy in Cystic Fibrosis is not currently available.
Objectives: To assess the in vivo efficacy of a method to adjust the dose of enzymatic supplement in CF extrapolated from previous in vitro digestion studies (theoretical optimal dose, TOD). Secondly, to assess how individual patient characteristics influence the expected coefficient of fat absorption (CFA) and thus to identify an individual correction factor to improve TOD.
Background: The New European guidelines have established the most updated recommendations on nutrition and pancreatic enzyme replacement therapy (PERT) in CF. In the context of MyCyFAPP project - a European study in children with CF aimed at developing specific tools for improvement of self-management - the objective of the current study was to assess nutritional status, daily energy and macronutrient intake, and PERT dosing with reference to these new guidelines.
Methods: Cross sectional study in paediatric patients with CF from 6 European centres.