Publications by authors named "Indukuri Hemalatha"
Article Synopsis
- Next-generation wireless networks rely on effective positioning, coverage, and connectivity to monitor regions and detect targets using wireless sensor networks (WSNs).
- Randomly deployed sensor nodes often lead to poor coverage and battery depletion creates gaps, necessitating optimal sensor placement to enhance monitorability, which this study addresses using an enhanced particle swarm optimization (EPSO) algorithm.
- The EPSO algorithm improves coverage by ensuring that sensor nodes are spaced apart and that each target is monitored, with results showing improved coverage conditions at various frequency bands, especially with a communication radius of 4 m compared to existing methods.
Respiratory syncytial virus (RSV), a negative-strand RNA virus, is the most common cause of epidemic respiratory disease in infants and young children. RSV infection of airway epithelial cells induces the expression of immune/inflammatory genes through the activation of a subset of transcription factors, including Nuclear Factor-κB (NF-κB). In this study we have investigated the role of the non canonical IκB kinase (IKK)ε in modulating RSV-induced NF-κB activation.
View Article and Find Full Text PDFRespiratory syncytial virus (RSV)-induced chemokine gene expression occurs through the activation of a subset of transcription factors, including Interferon Regulatory Factor (IRF)-3. In this study, we have investigated the signaling pathway leading to RSV-induced IRF-3 activation and whether it is mediated by intracellular reactive oxygen species (ROS) generation. Our results show that RSV infection induces expression and catalytic activity of IKKepsilon, a noncanonical IKK-like kinase.
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