Tears of Blood-An Uncommon Presentation of Rhinosporidiosis.

Rhinosporidiosis is a chronic granulomatous disease involving the mucous membranes of nose and nasopharynx caused by Rhinosporidium seeberi. Rhinosporidiosis involving the eye is known as Oculosporidiosis. Usually affected patients present with nasal obstruction with an associated mass, epistaxis and watery discharge.

Covid-19 Demographics from a Tertiary Care Center: Does It Depreciate Quality-of-Life?

Novel Coronavirus-disease-2019 (Covid-19) caused by the severe-acute-respiratory-syndrome coronavirus-2 (SARS-CoV-2) shows a rapid spread all over the world. It's still an ongoing pandemic with greater morbidity and mortality. In our study, we describe clinical features, and demographics of patients presenting to our tertiary care center with Covid-19 infection.

Polypharmacy and comorbidity status in the treatment of type 2 diabetic patients attending a tertiary care hospital: An observational and questionnaire-based study.

Purpose/aim: Diabetes mellitus is associated with several comorbid conditions. Thus, often, diabetic patients are prescribed multiple drugs. Although multiple drugs help to combat various diseases, they also increase the propensity of drug interactions and adverse drug reactions.

Amelioration of doxorubicin induced cardio-and hepato-toxicity by carotenoids.

Aim Of Study: The aim of this study is to explore the ability of the carotenoids (CARs) to offer protection against acute cardiotoxicity and hepatotoxicity induced by doxorubicin (DOX) (25 mg/kg) in tumor bearing Swiss albino mice.

Materials And Methods: Tumor bearing Swiss albino mice administered with DOX (25 mg/kg, i.p) and two doses of CARs (50 and 100 μg/kg).

Carcinosarcoma of the uterus-a single institution retrospective analysis of the management and outcome and a brief review of literature.

Uterine carcinosarcomas are highly aggressive tumors of the uterus associated with a poor prognosis. Though initially classified as sarcomas, now these tumors are classified as carcinomas. The management approach of carcinosarcomas has also changed from those used for high grade sarcomas to that used for managing high grade endometrial carcinomas.

Caspase-2 triggers Bax-Bak-dependent and -independent cell death in colon cancer cells treated with resveratrol.

Polyphenol phytoalexin (resveratrol), found in grapes and red wine is a strong chemopreventive agent with promising safety records with human consumption and unique forms of cell death induction in a variety of tumor cells. However, the mechanism of resveratrol-induced apoptosis upstream of mitochondria is still not defined. The results from this study suggest that caspase-2 activation occurs upstream of mitochondria in resveratrol-treated cells.