Publications by authors named "Indri Nogueira"
Article Synopsis
- The study aimed to assess the antibacterial effects of various chlorhexidine (CHX) concentrations against the bacteria Streptococcus mutans using two different testing methods: direct application (agar-diffusion) and indirect application (transdentinal diffusion with human dentin discs).
- The researchers prepared Petri dishes with S. mutans and tested different CHX concentrations (0.12%, 0.2%, 1%, 2%), phosphoric acid, and control groups, measuring the zones of bacterial growth inhibition after incubation.
- Results showed that higher CHX concentrations had greater antibacterial activity, with the most significant inhibition observed using 2% CHX on thinner dentin discs, indicating the effectiveness of CHX against S.
Unlabelled: Chlorhexidine gluconate (CHX) is recommended for a number of clinical procedures and it has been pointed out as a potential cavity cleanser to be applied before adhesive restoration of dental cavities.
Objective: As CHX may diffuse through the dentinal tubules to reach a monolayer of odontoblasts that underlies the dentin substrate, this study evaluated the cytotoxic effects of different concentrations of CHX on cultured odontoblast-like cells (MDPC-23).
Material And Methods: Cells were cultured and exposed to CHX solutions at concentrations of 0.
It has been demonstrated that chlorhexidine digluconate (CHX) is capable of eliminating bacteria that may remain lodged in dentin after mechanical caries removal. In addition, the use of CHX on acid-etched dentin before adhesive system application delays the resin-dentin interface degradation, maintaining the integrity of the adhesive restorations. Despite these advantages of using CHX in restorative dentistry, when applied on dentin, this chemical agent may diffuse across dentinal tubules to cause toxic effects to the pulp cells.
View Article and Find Full Text PDFCytotoxic effect of a 35% hydrogen peroxide bleaching gel on odontoblast-like MDPC-23 cells.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod
September 2009
Objective: This study evaluated transenamel and transdentinal cytotoxic effects of a bleaching gel on the MDPC-23 cell line.
Study Design: Discs obtained from bovine incisors were placed in a metallic device to simulate an in vivo pulp chamber. Groups were formed according to the enamel surface treatment: G1: 35% H(2)O(2) bleaching gel; G2: 35% H(2)O(2) bleaching gel + halogen light; G3: halogen light; and G4: control.
Purpose: To evaluate the cytotoxic effects of resin-based light-cured liners on culture of pulp cells.
Methods: Discs measuring 4 mm in diameter and 2 mm thick were fabricated from TheraCal (TCMTA), Vitrebond (VIT), and Ultrablend Plus (UBP). These specimens were immersed in serum-free culture medium (DMEM) for 24 hours or 7 days to produce the extracts.