Publications by authors named "Indranil Duttagupta"
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Synopsis of recent research by authors named "Indranil Duttagupta"
- Indranil Duttagupta's research predominantly focuses on the intersection of chemistry and biology, particularly in the development of innovative probes and inhibitors that address enzymatic and pathological mechanisms, including inflammatory diseases and signaling pathways.
- One notable study showcases the creation of nitroxide-based reporters to assess elastase activity, highlighting the role of neutrophil-derived proteases in pulmonary inflammation, thus signaling the potential for therapeutic intervention.
- Additional findings reveal the inhibition of Gli1 in the Hedgehog signaling pathway by piperazic acid derivatives, demonstrating their selective efficacy and minimal toxicity, which could lead to advancements in cancer treatment strategies.
