Publications by authors named "Indranil D Roy"

Article Synopsis
  • Maxillofacial reconstruction is complicated due to the region's intricate anatomy and its impact on patients' functionality and appearance.
  • Emerging technologies enable the use of patient-specific implants (PSIs) through virtual surgical planning, enhancing treatment options for those with maxillofacial defects and facilitating surgeries like orthognathic procedures.
  • While autogenous tissue remains the gold standard for reconstruction, PSIs reduce complications associated with donor sites, and future research aims to utilize PSIs as scaffolds for tissue engineering to restore lost anatomy.
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Pre-nasoalveolar molding (PNAM) was developed to reduce the severity of the initial cleft alveolar and nasal deformity. The nasoalveolar moulding appliance (NAM) consists of an intraoral moulding plate with nasal stents to mould the alveolar ridge and nasal cartilage concurrently. Use of the NAM technique also reduces surgical columella reconstruction and the resultant scar tissue in bilateral cleft lip and palate.

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Rationale: Congenital orofacial swellings in neonates are mainly limited to vascular malformations and neuroectodermal benign tumours. Congenital granular cell tumour (CGCT) is a rare condition affecting neonates with a prevalence rate of 6 in 1 million. Our report provides a brief review of diagnosis and management.

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Article Synopsis
  • Plasmablastic lymphoma (PBL) is a rare and aggressive type of large B-cell lymphoma often found in HIV-positive patients, commonly appearing in the oral cavity but not frequently reported as such in medical literature.
  • Oral PBL typically manifests as asymptomatic swelling with ulcerations and bleeding, and there is no established treatment protocol for this condition, resulting in a low five-year survival rate of around 33.5%.
  • The case presented highlights the importance of recognizing oral lesions as potential indicators of serious underlying health issues, as a suspicious ulcerated growth in the upper jaw was ultimately diagnosed as a rare HIV-related lymphoma rather than carcinoma.
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Carotid- Cavernous Fistula (CCF) represents an aberrant vascular communication at the skull base between the high-flow carotid arterial system and the low-flow venous channels within the cavernous sinuses of the sphenoid bone. Benjamin Travers, in the year 1809, described this condition as "pulsating exophthalmos". This case is a presentation of a carotid cavernous fistula in an operated case of maxillofacial injury as a late complication.

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Article Synopsis
  • MNTI is a rare, benign tumor often found in infants, mainly affecting the maxilla, and originates from neural crest cells, but can behave aggressively and mimic cancer.
  • A two-year-old girl with a growing upper lip swelling underwent successful tumor resection, and histological tests confirmed it as MNTI.
  • Post-surgery, she healed well without recurrence, highlighting that early diagnosis and conservative treatment lead to positive outcomes for MNTI.
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Background: The coronavirus disease 2019 (COVID-19) pandemic has posed another serious threat, mucormycosis infection, affecting the maxilla and orbitocerebral region. This condition has not spared world population from its merciless claws. This article addresses the challenges faced by the maxillofacial surgeons in setting the protocols from preoperative diagnosis, surgical management to postoperative care, including short-term and long-term rehabilitation.

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Background: Amyloidosis is a distressing and infrequent condition caused by accumulation of abnormally folded proteins as aggregates in the extracellular tissue spaces of the body, leading to destruction of organ structure and function. Presentation of Oral Amyloidosis is generally a rare phenomenon, tongue being the most common site to manifest the disease process. Accurate recognition of the amyloid protein and its sub typing is absolutely critical for clinical management and to assess prognosis such as to avoid misdiagnosis and unwanted, potentially harmful treatment.

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Advances in periodontal plastic surgical procedures have led to achieve predictable root coverage outcomes for the recession defects. However, little has been reported and emphasised over management of palatal recession defects. The root coverage surgical procedures used for coverage of palatal recession defect are technically challenging in terms of accessibility and graft coverage.

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Article Synopsis
  • Central adenoid cystic carcinoma (ACC) of the mandible is a rare tumor that arises from minor salivary glands and can mimic other dental diseases, making it hard to diagnose accurately.
  • ACC is known for its long clinical progression, tendency to invade nerves, high recurrence rates, and potential for spreading to distant sites.
  • The study highlights a unique case of ACC in an unusual location in the mandible, while emphasizing the importance of thorough diagnostic evaluations and long-term monitoring due to its characteristic histopathological features.
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Background: Trigeminal neuralgia is a painful disease that has been afflicting mankind since time immemorial. The etiology and pathophysiology have been widely studied but poorly understood. There are well-documented researches analyzing ultrastructural changes in trigeminal root specimens obtained following microvascular decompression surgery.

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Purpose: Elongated styloid process results in severe cranio-facial/cervico-facial pain. The purpose of this study is to determine the efficacy of treatment outcomes using transcervical approach in the management of styloid-stylohyoid syndrome/styloid syndrome.

Study Design: This is a retrospective cohort study.

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Objective: The aim of the systematic review was to analyse the available evidence in order to assess the efficacy of dextrose prolotherapy in improving outcomes in temporomandibular joint (TMJ) hypermobility patients as compared to placebo.

Methods: An electronic search of PubMed, Scopus, CENTRAL and Google scholar databases was performed for English language papers published up to February 2018. Randomised clinical trials (RCTs) and controlled clinical trials (CCTs) comparing dextrose prolotherapy with placebo for TMJ hypermobility were included.

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Background: Temporomandibular joint (TMJ) ankylosis is one of the most disruptive maladies afflicting the masticatory system. The characteristic feature is the formation of bony mass bridging condyle with glenoid fossa. The exact pathogenesis is, however, not completely understood.

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Article Synopsis
  • The study aimed to analyze the effects of mandibular advancement via distraction osteogenesis on the posterior airway space (PAS) and mandibular plane hyoid (MPH) distance in patients with mandibular hypoplasia.
  • In a study involving 25 patients aged 15-30 years, results showed a significant reduction in MPH distance by 32% and an increase in PAS by 75%, with the average distraction achieved being 14.50 mm.
  • While MPH and SNB measurements showed statistically significant changes, the increase in PAS was not statistically significant; however, it suggests potential clinical benefits, particularly for treating obstructive sleep apnea.
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Purpose: Lateral displacement of fracture zygomaticomaxillary complex (ZMC) can cause significant increase in orbital volume leading to enophthalmos. The aim of this study was to radiologically evaluate the efficacy of sphenozygomatic (SZ) suture fixation for restoration of orbital volume after elevation of the temporalis in cases of fracture ZMC where the fixation of zygomatic arch (ZA) was deemed necessary through latero-posterior approach.

Materials & Methods: 43 operated cases of fracture ZMC using 4-point fixation were divided into two groups.

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Breach in the palatal vault leading to an abnormal communication between oral and nasal cavity is known as oro-nasal communication. It is an uncommon presentation in day-to-day clinical practice except in some patients of cleft lip and palate.Etiology may be congenital or acquired.

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Article Synopsis
  • Acquired Brown's syndrome is a rare condition that can lead to complications like fibrosis if treatment is delayed.
  • The prognosis for vertical diplopia, which is double vision in the vertical plane, remains uncertain after such delays.
  • The case reported is the first documented instance of successfully treating superior oblique muscle entrapment due to an orbital roof fracture in a 22-year-old male using a delayed release technique.
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Post radiation trismus severely reduces the quality of life. Radiation causes fibrosis of muscles of mastication resulting in severe restriction of mouth opening. Treatment options are limited as most of the local flaps are in the radiation zone.

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Article Synopsis
  • The study assesses the use of strip craniectomy paired with distraction osteogenesis for treating craniosynostosis in two selected cases.
  • After a delay of 4 days, distraction was executed using intraoral devices, achieving 25-28 mm separation of the skull segments.
  • Results showed increased skull size, enhanced cognitive function, and reduced symptoms associated with elevated intracranial pressure, indicating that this combined treatment is effective.
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Article Synopsis
  • Patients with cleft lip and palate often experience midface hypoplasia, traditionally treated with orthognathic surgery, which has issues with relapse; this study investigates maxillary distraction osteogenesis using a rigid external device (RED) as a potentially more stable alternative.
  • Nine patients underwent maxillary advancement following a specific surgical procedure, with outcomes assessed through imaging at three stages: before distraction, immediately after, and one year later.
  • Results indicated a successful average midface advancement of 13.4 mm with stable bone formation and no significant complications, suggesting the RED technique is an effective option for improving maxillary positioning over time.
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Objectives: The aim of this study was to compare the outcome of reconstruction options adopted for the management of temporomandibular joint (TMJ) ankylosis.

Patients And Methods: This retrospective cohort study consisted of a sample of patients with TMJ ankylosis diagnosed clinically and radiologically. Depending upon the reconstruction provided, the cases were divided into 2 groups.

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