Publications by authors named "Indrakanti Ramesh Babu"
Mol Syst Biol
October 2018
Article Synopsis
- Ribonucleoside modifications on tRNAs play a key role in regulating cell functions and stress responses, particularly during the developmental cycle of erythrocytic stages.
- During this cycle, 22 out of 28 tRNA modifications showed a coordinated increase, indicating tRNA maturation aligns with enhanced translation needs from the ring to trophozoite stages.
- The study also found that late-stage proteins exhibit a significant codon bias connected to changes in tRNA modifications, suggesting that these modifications improve the translation efficiency of important genes linked to the parasite's development and disease progression.
