Troponin testing in routine primary care: observations from a dynamic cohort study in the Amsterdam metropolitan area.

Objectives: Troponin testing is indicated in the diagnostic work-up of acute coronary syndrome (ACS) and incorporated in risk stratification pathways. This study aims to gain insights on the use, outcomes, and diagnostic accuracy of troponin testing in routine primary care; a setting that is understudied.

Methods: Routine data were used from the academic primary care network in the Amsterdam metropolitan area (968,433 patient records).

The effect of additional drug therapy as metaphylaxis in patients with cystinuria: a systematic review.

Introduction: To systematically review the effect of additional drug therapy as metaphylaxis in patients with cystinuria.

Evidence Acquisition: A literature search of three databases (MEDLINE, Embase and the Cochrane Library) was performed according to the PRISMA-guidelines enclosing articles published up to May 2019. A total of 1117 articles were screened.