Publications by authors named "Indra Limbu"
Am J Case Rep
January 2022
Article Synopsis
- Blastomycosis is an opportunistic fungal infection primarily affecting immunocompromised individuals, often leading to severe complications like pneumonia and respiratory distress if not treated early.
- A case study details a 74-year-old man who, despite being treated with amphotericin B for blastomycosis, succumbed to respiratory complications after 5 days in the hospital.
- The disease's nonspecific symptoms can result in delayed diagnosis, particularly in vulnerable populations, contributing to a higher mortality rate.
Article Synopsis
- Vancomycin is rarely linked to thrombocytopenia, and the study aimed to investigate if it causes this condition through immune mechanisms by identifying vancomycin-dependent antibodies in affected patients.
- In a 5-year analysis, they found these antibodies in 34 patients, with severe thrombocytopenia leading to significant bleeding in nearly one-third of them, but recovery was noted once vancomycin was discontinued.
- The presence of these antibodies in patients with low platelet counts, and their absence in those who remained stable, suggests a clear causal relationship between vancomycin and immune thrombocytopenia.
