Amphetamine-like Deferiprone and Clioquinol Derivatives as Iron Chelating Agents.

The accumulation of iron in dopaminergic neurons can cause oxidative stress and dopaminergic neuron degeneration. Iron chelation therapy may reduce dopaminergic neurodegeneration, but chelators should be targeted towards dopaminergic cells. In this work, two series of compounds based on 8-hydroxyquinoline and deferiprone, iron chelators that have amphetamine-like structures, have been designed, synthesized and characterized.

#JunkScience: Investigating pseudoscience disinformation in the Russian Internet Research Agency tweets.

Recent research has identified anti-vaccination propaganda in the so-called Russian Troll Tweets strongly associated with the 2016 US Presidential election. This study builds on this: hypothesising that if vaccination content was found in the sample, the Russia Tweets would be likely to contain other science content, and perhaps, similar pseudo or anti-science messages. As well as vaccination, climate change, genetically modified organisms, Ebola, flat Earth beliefs (flat Earthism) and Zika were found in the Russia tweets.