Publications by authors named "Inden Y"
Background: Visualizing the specific regions where atrial fibrillation (AF) is maintained is crucial for effective treatment, but it remains challenging in clinical practice. We aimed to address this challenge by developing a mapping approach focused on the cycle length (CL) and its gradient (CL-gradient).
Methods: In 105 patients undergoing initial ablation for persistent AF, pre-ablation CARTOFINDER data were utilized to create maps based on three indicators: (1) CL, the atrial frequency during AF calculated using CARTOFINDER; (2) Short CL, encompassing CLs within 5 ms of the minimum CL; and (3) CL-gradient, the CL range within a 6 mm radius.
A His-bundle (HB) capture threshold rise is still a significant concern in permanent His-bundle pacing (HBP). We present a case where an abrupt increase in HB threshold and loss of capture occurred even after 3.5 years of stable permanent HBP for an atrioventricular block.
View Article and Find Full Text PDFBackground: Atrial fibrillation (AF) and heart failure (HF) often coexist, leading to increased mortality. A cryoballoon-based approach is a potential treatment for patients with HF because of its safety and efficacy.
Objectives: The authors sought to evaluate the optimal timing of cryoballoon ablation after the first clinical diagnosis of AF and its prognosis for patients with HF.
Article Synopsis
- Patients with subcutaneous implantable cardioverter-defibrillators (S-ICDs) experience oversensing episodes (OS) more frequently than those with traditional transvenous ICDs, indicating a need for better detection methods.
- A study of 21 patients found that 28.6% experienced OS, particularly among those with Brugada/J wave syndrome, and determined that a significantly lower QRS amplitude in the synthesized V7 lead (synV7) was linked to OS incidence.
- The study suggests that a synV7 QRS amplitude of less than 0.61 mV can effectively predict the occurrence of OS, highlighting the need for monitoring this parameter in patients with S-ICDs.
Article Synopsis
- * After being treated with SGLT2is and other heart failure therapies, the patient's heart failure symptoms stabilized, and his electrocardiogram showed a significant reduction in QRS duration from 143 ms to 112 ms over six months.
- * This case suggests that SGLT2is can lead to electrical and mechanical improvements in heart function, indicating the importance of exploring treatment options alongside considering cardiac resynchronization therapy (CRT).
Background: TactiFlex is a next-generation catheter that is being used increasingly in ablation-treatment strategies. The purpose of this study was to investigate the differences in ablation lesions when the ablation power, time, and perfusion flow are varied with TactiFlex and TactiCath catheters.
Methods: The TactiFlex and TactiCath catheters were contacted perpendicularly/obliquely/parallel to the swine myocardium at varying powers (30, 40, and 50 W), time points (10, 15, 20, 25, 30, and 40 s), and forces (5, 10, 15, 20, and 30 g); the depth, width, and area of each lesion were measured, and the number of steam pops that occurred was counted.
Background: Outcomes in patients with relatively high His-bundle (HB) capture thresholds at implantation are unknown. This study aimed to compare changes in the HB capture threshold and prognosis between patients with a relatively high threshold and those with a low threshold.
Methods And Results: Forty-nine patients who underwent permanent HB pacing (HBP) were divided into two groups: low (<1.
Background: The fibrosis-5 (FIB-5) index is a noninvasive marker for assessing the progression of liver fibrosis and predictor in patients with heart failure (HF). This study investigated the association between the FIB-5 index and response to cardiac resynchronization therapy (CRT) and evaluated its predictive value for prognosis.
Methods: In total, 203 patients who underwent CRT/CRT-defibrillator (CRT-D) implantation were retrospectively included.
Background: The Mt FUJI study was a multicenter, prospective, randomized, single-blind, controlled trial comparing delivery catheter-based and stylet-based right ventricular (RV) lead placement at the RV septum. This study extended the follow-up duration to 1 year after implantation.
Methods: Seventy patients with pacemaker indications for atrioventricular block were randomly assigned to the delivery catheter and stylet groups.
Introduction: The underlying risks of asymptomatic embolization during high-power short-duration (HPSD) ablation for atrial fibrillation remain unclear. We aimed to evaluate microembolic signals (MESs) during HPSD ablation with power settings of 50 and 90 W in comparison with those during cryoballoon (CB) ablation using a novel carotid ultrasound-Doppler system that classifies solid and air bubble signals using real-time monitoring.
Methods And Results: Forty-seven patients underwent HPSD ablation using radiofrequency (RF), and 13 underwent CB ablation.
Unlabelled: Atrial tachyarrhythmias occurring after transcatheter atrial septal defect closure are not uncommon; however, those related to device stimulation are rare. Herein, a case involving a 24-year-old female, who developed drug-refractory atrial tachycardia during the early postoperative period, is reported. The results of electroanatomical mapping could eventually be obtained from both atria.
View Article and Find Full Text PDFArticle Synopsis
- - The study investigates the effectiveness of using real-time ultrasound guidance for venous closure with suture-mediated vascular closure devices (VCDs) in patients undergoing catheter ablation procedures.
- - Results showed that ultrasound guidance significantly lowered the rate of device failure and overall access site-related complications compared to traditional methods without ultrasound assistance.
- - Patients who received ultrasound-guided closure experienced faster recovery times, allowing them to ambulate more quickly than those who did not receive this guidance.
Background: The TactiFlex SE catheter (TFSE, Abbott) with a contact force (CF) sensor and a laser-cut irrigated-tip has recently become available but lacks a lesion quality marker. This study aimed to explore distinctions in lesion characteristics between the TFSE and the ThermoCool SmartTouch SurroundFlow catheter (STSF, Biosense Webster), which utilizes a porous irrigated tip, and to assess the most effective application settings for the TFSE.
Methods: Lesions were generated using varying settings of radiofrequency power (30-50 W), CF (10-20 g), application duration (10-40 s), and catheter orientation (perpendicular or parallel) in an ex vivo porcine model.
Article Synopsis
- Torsades de Pointes (TdP) is a type of polymorphic ventricular tachycardia associated with long QT syndrome, but can also occur in conditions like Brugada syndrome without prolonged QT intervals.
- The initiation of TdP is linked to early afterdepolarizations and maintained by reentrant activities due to varying repolarization rates, though research on its maintenance mechanisms is still limited.
- Recent studies using a rabbit model suggest that prolonged refractoriness from enhanced late sodium currents might play a key role in TdP, prompting investigations into new factors like the Na1.8 sodium channel in its underlying mechanisms.
Introduction: Intrinsic antitachycardia pacing (iATP) is a novel automated antitachycardia pacing (ATP) that provides individual treatment to terminate ventricular tachycardia (VT). However, the clinical efficacy of iATP in comparison with conventional ATP is unknown. We aim to compare the termination rate of VT between iATP and conventional ATP in patients with implantable cardioverter-defibrillators using a unique setting of different sequential orders of both ATP algorisms.
View Article and Find Full Text PDFBackground: Currently, the standard curative treatment for ventricular tachycardia (VT) and ventricular fibrillation (VF) is radiofrequency catheter ablation. However, when the VT circuit is deep in the myocardium, the catheter may not be delivered, and a new, minimally invasive treatment using different energies is desired.
Methods: This is a protocol paper for a feasibility study designed to provide stereotactic radiotherapy for refractory VT not cured by catheter ablation after at least one catheter ablation.