Publications by authors named "Incilay Kalay Yıldızhan"
Background: Mycosis fungoides (MF) is the commonest form of primary cutaneous T-cell lymphoma. Progression is slow, with frequent relapses. Data for predicting early-stage MF progression and recurrence are inadequate.
View Article and Find Full Text PDFBackground/purpose: Interferon (IFN)-a is often used in combination with psoralen plus ultraviolet A (PUVA) in patients with mycosis fungoides (MF) refractory to skin-targeted therapies in early or advanced stages. The main objective is to evaluate the effectiveness of combined PUVA and low-dose IFN-α-2a therapy in patients with early- and advanced-stage MF.
Methods: Sixty-eight patients who received a combination of PUVA twice or thrice a week and INF-a 3 MU thrice a week for at least 3 months were reviewed retrospectively.
Introduction: Increasing the numbers of patch testing in suspected children increases the rate of diagnosis of allergic contact dermatitis and the identification of clinically relevant allergens.
Objective: The aim of this study was to identify the most frequently observed allergens among Turkish children and adolescents patch-tested in 2013-2023.
Methods: The patch test results of 160 patients (age ≤18) were analyzed retrospectively.
Article Synopsis
- The study aimed to explore skin changes in patients with acromegaly, a condition often revealed through dermatological symptoms, and examine how these changes relate to disease remission and other hormonal disorders.
- Involving 278 acromegaly patients across 14 healthcare centers, dermatological evaluations revealed common skin conditions like skin tags (52.5%), cherry angiomas (47.4%), and varicose veins (33%).
- Significant associations were found between certain skin conditions and hormonal issues, such as higher rates of diabetes and hypothyroidism in patients with varicose veins, while hypertrichosis was more common in patients who had not achieved remission.
Background: Previous reports indicate that juvenile Behçet's disease (BD) may have a different course than adult BD. However, as a direct comparison with adult Behçet patients has only been made in a limited number of studies, the issue is still controversial.
Objectives: The primary aim of our study was to compare clinical manifestations in a large cohort of juvenile and adult Behçet patients registered in a single centre.
Introduction: The COVID-19 pandemic drastically changed the priorities in healthcare services; outpatient management of acne has changed during this period.
Objectives: We aimed to investigate treatment practices, outcomes and identify modified follow-up schedules applied during the pandemic.
Methods: The patients who were admitted to dermatology outpatient clinic between March 13 and July 13, 2020, were included.
Article Synopsis
- - The study aimed to determine the incidence, demographics, and clinical characteristics of pemphigoid diseases in Turkey, as existing data were limited.
- - Researchers analyzed 295 patients diagnosed with pemphigoid over one year, finding a higher prevalence of bullous pemphigoid, which accounted for 93.2% of cases, with an overall incidence rate of 3.55 cases per million years.
- - The study highlighted that gliptin derivative drugs might be a common trigger for bullous pemphigoid, and cardiovascular (27.8%) and neurological (23.7%) diseases were frequently observed alongside these conditions.
Sterol-C4-methyl oxidase (SC4MOL) deficiency was recently described as an autosomal recessive cholesterol biosynthesis disorder caused by mutations in the MSMO1 (sometimes also referred to as SC4MOL) gene. To date, 5 patients from 4 unrelated families with SC4MOL deficiency have been reported. Diagnosis can be challenging as the biochemical accumulation of methylsterols can affect global development and cause skin and ocular pathology.
View Article and Find Full Text PDFBackground: Prevalences of sensitivity to contact allergens change over time as a result of variations in allergen exposure.
Objectives: The aim of the study was to describe trends in sensitisation to allergens of the European baseline series in Turkey between 2013 and 2019.
Methods: The patch test results of 1309 patients with suspected allergic contact dermatitis (ACD) were analysed retrospectively, and the prevalence of contact allergies to European baseline series allergens was compared with previous data (for 1998-2005).
Folliculotropic mycosis fungoides (FMF) is characterized by a broad clinical spectrum and worse prognosis compared to classical MF. This study aimed to evaluate the clinical characteristics, treatment modalities and long-term outcome and risk factors for progression and survival of FMF patients. We conducted a single-center retrospective study and reviewed 53 patients diagnosed with FMF between 1990 to 2019 in a referral center at Ankara University, Turkey.
View Article and Find Full Text PDFBackground And Objective: Less than 5% of cases of mycosis fungoides (MF) present with a cytotoxic/suppressor CD8 phenotype. This study aimed to evaluate the clinical characteristics, treatment modalities, and clinical course in CD8 MF patients.
Methods: In a retrospective analysis of 353 MF patients in a referral center at Ankara University, Turkey, 29 patients that were diagnosed with CD8 MF were included in the study.
Malignant syphilis (also known lues maligna) is a rare and severe variant of secondary syphilis. It is most commonly seen in patients who are infected with human immunodeficiency virus (HIV), and rarely, it can occur in immunocompetent individuals. The exact mechanism of the development of malignant syphilis is not clear.
View Article and Find Full Text PDFObjectives: This study aims to compare the sensitivity of the intradermal application of the pathergy test with the "three-step pathergy test".
Patients And Methods: The study included 60 patients with Behçet's disease (BD) (23 males, 37 females; mean age 33.9±9.