Publications by authors named "Inchara Y Kalegowda"
Nail involvement is seen in 10% of lichen planus patients, with a subset developing severe destruction of the nail matrix. Nail biopsy is a complex procedure usually done when nails are the only site of involvement. The pathology of nail lichen planus (NLP) has been the subject of very few studies.
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- Darier disease (DD) is a rare genetic skin condition primarily documented through case reports, prompting a study to systematically examine its histopathologic features in skin biopsies over 12 years.* -
- The study reviewed biopsies from 16 patients, primarily in their 30s, revealing common symptoms like hyperpigmented papules and plaques, with notable histological features including suprabasal acantholytic clefts and various unusual patterns.* -
- The study emphasizes the importance for pathologists to recognize the diverse histopathological variations of DD, particularly in atypical cases, while acknowledging its limitation due to a small sample size.*
Congenital pouch colon is an uncommon anomaly worldwide and is usually associated with anorectal malformations. Imperforate anus with a large air fluid level on the abdominal x ray suggests the diagnosis. Most cases are diagnosed in neonates and an early management limit complications.
View Article and Find Full Text PDFBIOCHIP mosaics for indirect immunofluorescence in cutaneous vesiculobullous diseases provide antibody profiles in a single run and can be an alternative to performing multistep assays. There is scanty data regarding their utility. BIOCHIP tests performed over 4 years were compared with biopsy and/or direct immunofluorescence (DIF).
View Article and Find Full Text PDFClonal seborrheic keratosis (CSK) and pagetoid Bowen disease (squamous cell carcinoma in situ) (PBD) share similar histological features making it sometimes difficult to differentiate the 2. The study group included 29 and 13 cases of CSK and PBD, respectively. Both groups were examined histopathologically (suprabasal mitotic figures, broad rete ridges, crowding of nuclei, nuclear pleomorphism, necrotic keratinocytes, parakeratosis, and dermal inflammation) and immunohistochemically (CK10, Ki-67, and p16).
View Article and Find Full Text PDFA 55-year-old woman presented with a 5-year history of livedo racemosa on her limbs. Histology showed vasculitis of medium-sized arteries with a circumferential, hyalinised, intraluminal fibrin ring. Her laboratory investigations did not indicate any underlying systemic disease.
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