Publications by authors named "Inamasu J"

Article Synopsis
  • A study investigated whether there are left (Lt) and right (Rt) differences in the occurrence of ruptured middle cerebral artery bifurcation (MCAB) aneurysms among patients.
  • Analyzed clinical data from 99 patients showed 42 with Lt and 57 with Rt ruptured aneurysms, indicating that Rt ruptures are 1.36 to 1.40 times more common than Lt ones.
  • Despite the frequency difference, no significant variations were found in demographic, clinical, or outcome factors between the two groups, suggesting further research is needed to understand the anatomical reasons behind these disparities.
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Hemorrhagic strokes are considered as contraindications of extracorporeal membrane oxygenation (ECMO) therapy because of anticoagulant administration and ECMO-associated coagulopathy. We present a rare case of successful microsurgical clipping under ECMO for a poor-grade subarachnoid hemorrhage (SAH) patient with severe neurogenic pulmonary edema (NPE). A 50-year-old man presenting with the sudden loss of consciousness was diagnosed with poor-grade SAH with severe NPE, and was intubated.

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It has been shown that living alone is one of the risk factors for unfavorable outcomes in ischemic stroke patients, mostly due to delay in receiving appropriate treatment. A single-center retrospective observational study was conducted to evaluate whether living alone was associated with unfavorable outcomes in aneurysmal subarachnoid hemorrhage (SAH) patients. Among 451 SAH patients admitted to our institution between January 2013 and December 2022, 43 patients who lived alone had sustained SAH at home (group A) and 329 patients who lived with family had sustained SAH at home (group F).

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Article Synopsis
  • Aneurysmal subarachnoid hemorrhage (aSAH) is a serious condition that can happen during sleep, but it wasn't thought to be caused by sleep itself until now.
  • A study looked at 623 patients and found that those who had aSAH while sleeping were more likely to have diabetes and use blood-thinning medications than those who had it while awake.
  • The researchers want to learn more about how health conditions like diabetes and sleep troubles could impact aSAH during sleep to understand the problem better.
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In this study, we report on a previously healthy 44-year-old man who underwent an open biopsy under general anesthesia for a tumorous lesion found in his left frontal lobe via a small supratentorial craniotomy. While both postoperative course and brain computed tomography (CT) scans had been considered unremarkable, the patient became stuporous on postoperative day (POD) 4. A brain CT obtained on that day showed a subdural hematoma with marked brain shift which we thought might have been due to postoperative bleeding; he was immediately brought to an operating theater for hematoma removal.

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We describe a rare case of sacral epidural arteriovenous fistulas (edAVFs) with atypical clinical course of treatment. A 78-year-old man with a history of spinal surgery presented progressive gait disturbance and urinary incontinence. Spinal angiography demonstrated a sacral spinal AVF fed by bilateral lateral sacral arteries, draining to the venous pouch with subdural drainage.

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Objective: The objective of the study was to clarify the prevalence of and factors associated with changes in patients' outcomes between discharge and 3 months after the onset of aneurysmal subarachnoid hemorrhage (aSAH). Additionally, the World Federation of Neurosurgical Societies (WFNS) and modified WFNS (mWFNS) scales were compared.

Methods: The data of curatively treated patients with aSAH, collected prospectively in the mWFNS scale study between January 2010 and December 2012, were analyzed retrospectively.

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A 68-year-old woman with Parkinson's disease, who had previously undergone Roux-en-Y gastrojejunostomy for early gastric cancer, complained of wearing-off and troublesome dyskinesia that had progressed over 7-years. After the introduction of levodopa-carbidopa intestinal gel therapy (LCIG) by nasojejunal tube, she had a good clinical response. Percutaneous endoscopic gastrostomy with a jejunal extension tube was difficult in this case, due to lack of gastrostomy site and fibrous postoperative adhesion.

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Article Synopsis
  • A 12-year-old boy had a bleeding problem in his brain from a small blood vessel issue called micro-AVM.
  • Doctors used special imaging to find the problem and started treatment with a method called transarterial embolization, which helped fix the issue completely.
  • The study suggests that careful imaging can help understand and treat micro-AVM, and surgery should be there in case other treatments don't work completely.
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Seizures are common neurological emergencies that occasionally cause prolonged impairment of consciousness. The aim of this retrospective single-center study is to clarify factors associated with prolonged impairment of consciousness for admitted adult patients investigating patient backgrounds, blood tests, electroencephalographic patterns, and MRI findings. The patients who were admitted to the hospital due to epileptic seizures were classified into two groups: (1) early recovery group, in which patients recovered their consciousness within 6 hr, and (2) delayed recovery group, in which patients showed impairment of consciousness more than 6 hr.

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Article Synopsis
  • Isocitrate dehydrogenase (IDH) wild-type diffuse astrocytic tumors are commonly diagnosed as glioblastomas (GBMs), with a lower myoinositol to total choline (Ins/Cho) ratio in GBMs compared to IDH-mutant gliomas.
  • A study was conducted to see if a low Ins/Cho ratio correlates with poorer progression-free survival (PFS) and overall survival (OS) in patients with IDH-wild-type GBMs.
  • Results showed that patients with a low Ins/Cho ratio had significantly shorter PFS and OS, suggesting that the Ins/Cho ratio may serve as a useful prognostic marker for these tumors.
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Seizures are common in patients with gliomas; however, the mechanisms of epileptogenesis in gliomas have not been fully understood. This study hypothesized that analyzing quantified metabolites using magnetic resonance spectroscopy (MRS) might provide novel insights to better understand the epileptogenesis in gliomas, and specific metabolites might be indicators of preoperative seizures in gliomas. We retrospectively investigated patient information (gender, age at diagnosis of tumor, their survival time) and tumor information (location, histology, genetic features, and metabolites according to MRS) in patients with gliomas.

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A soft tissue defect is often an unavoidable consequence of various surgical procedures or a result of trauma. Recently, intraoperative use of xenograft as a patch to the soft tissue defect has become popular with various products available in the market. In this study, mechanical properties of the OrthADAPT™ Bioimplants (Pegasus Biologics, Irvine, CA), new xenograft products composed of collagen from equine pericardium, were evaluated individually and against an existing bioimplant product.

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Background: Although the number of seemingly healthy subjects who suffer a minor stroke increases, there are no data on how frequently they sustain another stroke while driving.

Methods: A single-center, retrospective study was conducted to clarify the clinical characteristics of driving-related stroke occurring as a recurrent stroke by analyzing data prospectively acquired between January 2009 and June 2019 on 3452 acute stroke patients.

Results: One hundred-thirty five patients (85 ischemic stroke [IS] and 50 hemorrhagic stroke [HS]) had suffered a driving-related stroke.

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Purpose: Two-wheeled motor vehicles are dichotomized into mopeds and motorcycles (MCs) based on their engine capacity. While efforts have been made, mostly by European researchers, to evaluate the possible difference in the frequency/severity of riders' traumatic brain injury (TBI) between the two categories, the results have been inconsistent.

Methods: To evaluate whether such differences exist in Japan, a single-center, retrospective observational study was conducted on two-wheeled motor vehicle riders wearing a helmet during high-energy road traffic accident (RTA).

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A 24-year-old man, who had been treated for 3 years as Asperger syndrome in adolescence due to behavioral disturbances, lack of social awareness and inability to socialize, was referred to our hospital shortly after tremors developed. On the basis of clinical features, laboratory findings and the brain MRI, a diagnosis of Wilson's disease (WD) was made. WD was further confirmed by genetic testing (the mutation of ATP7B gene).

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We present a rare case of traumatic acute subdural hematoma (SDH) in which intracranial hypotension (IC) secondary to cerebrospinal fluid (CSF) leakage at the lumbar spine caused delayed neurological deterioration. A 70-year-old male sustained a head injury after ground-level fall and was brought to our institution. A brain computed tomography (CT) showed a thin acute SDH with mild brain shift, and conservative management was initiated.

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Objectives And Background: Arterial dissection (AD) of the vertebral artery (VA) or its branches may cause ischemic stroke of the posterior circulation. However, clinical and radiological characteristics of patients with AD-related cerebellar infarction (CI) have rarely been reported.

Methods: Forty-nine patients with CI admitted to our department from April 2008 to March 2015 were identified from our database.

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Article Synopsis
  • This study looked at how often people have seizures while driving by analyzing data from 658 seizure patients who visited the emergency room.
  • Out of the group, 19 patients (around 3%) had seizures while driving, with similar rates in those diagnosed with epilepsy and those who weren't.
  • Most of the patients who had seizures while driving caused car accidents, and the researchers noted that studying seizures in people without epilepsy is important because it happens more than previously thought.
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Purpose: Seatbelts and airbags are the most important devices protecting drivers from cervical spine injury (CSI) following motor vehicle collisions (MVCs). However, there have been few reports on the radiographic characteristics of CSI sustained by restrained, airbag-deployed drivers.

Methods: A single-center, retrospective observational study was conducted using prospectively acquired data.

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Article Synopsis
  • A 66-year-old man had a big bulge (aneurysm) in a blood vessel in his brain, which was causing him to feel weak in his right leg.
  • He had surgery to fix it by clipping the bulge, but after waking up, he had trouble moving his right side even more because of extra swelling around the aneurysm.
  • Luckily, after a couple of weeks and some rest, he got better and his symptoms went away completely.
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Background: Although K-cars, small four-wheeled vehicles with an engine capacity of <660 cc, have been used almost exclusively in Japan, they have recently become increasingly popular in other countries. Therefore, reporting the characteristics of bodily injuries sustained by K-car drivers after road traffic accidents (RTAs) may be important not only for health professionals but also for car manufacturers.

Methods: A single-center, retrospective observational study was conducted using prospectively acquired data.

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