Publications by authors named "In-Yeong Jeong"
J Toxicol Pathol
January 2022
Article Synopsis
- The study investigates the effects of a water extract commonly used in herbal medicine on rat stomach tissue, focusing on cell proliferation (Ki-67) and apoptosis (Caspase-3) due to induced squamous cell hyperplasia.
- Rats were treated with varying doses of the extract, with significant hyperplasia observed at the highest dose of 3,000 mg/kg, but this condition fully resolved after a 4-week recovery period.
- While Caspase-3 levels rose significantly in the high-dose group, Ki-67 expression remained similar across all groups, leading to the conclusion that the induced squamous cell hyperplasia is a non-adverse effect and not an abnormal growth response in rats.
