Rotational vertebral artery occlusion: mechanisms and long-term outcome.

Background And Purpose: To elucidate the mechanisms and prognosis of rotational vertebral artery occlusion (RVAO).

Methods: We analyzed clinical and radiological characteristics, patterns of induced nystagmus, and outcome in 21 patients (13 men, aged 29-77 years) with RVAO documented by dynamic cerebral angiography during an 8-year period at 3 University Hospitals in Korea. The follow-up periods ranged from 5 to 91 months (median, 37.

Randomized clinical trial for geotropic horizontal canal benign paroxysmal positional vertigo.

Objectives: To determine the immediate and long-term therapeutic efficacies of barbecue rotation and Gufoni maneuvers, a randomized, prospective, and sham-controlled study was conducted in patients with the geotropic type of benign paroxysmal positional vertigo involving the horizontal semicircular canal (HC-BPPV).

Methods: In 10 nationwide dizziness clinics in Korea, 170 consecutive patients (107 women, age range 11-97 years, mean age ± SD 61 ± 15 years, median = 61 years) with geotropic HC-BPPV were randomly assigned to barbecue rotation (n = 56), Gufoni (n = 64), or sham maneuver (n = 50). An immediate response was determined within 1 hour after a maximum of 2 trials of each maneuver on the visit day.

Novel CLCN1 mutations and clinical features of Korean patients with myotonia congenita.

Myotonia congenita (MC) is a form of nondystrophic myotonia caused by a mutation of CLCN1, which encodes human skeletal muscle chloride channel (CLC-1). We performed sequence analysis of all coding regions of CLCN1 in patients clinically diagnosed with MC, and identified 10 unrelated Korean patients harboring mutations. Detailed clinical analysis was performed in these patients to identify their clinical characteristics in relation to their genotypes.

Isolated nodular infarction.

Background And Purpose: Isolated nodular infarction has rarely been described in human. The purpose of this study is to report clinical and laboratory findings of isolated nodular infarction.

Methods: Eight patients with isolated nodular infarction were recruited from 6 hospitals in Korea.

Delayed quick spins after vestibular nerve section respond to anticonvulsant therapy.

Objective: To describe the clinical features of patients with failed vestibular nerve section that have a response to anticonvulsant medication.

Study Design: Retrospective case review.

Setting: Ambulatory tertiary referral center.