Publications by authors named "In-Hae Lee"

Background: Aedes albopictus (Skuse 1894) mosquitoes can transmit deadly arboviruses and are globally invasive due to their ability to survive in both tropical and temperate climates. Although adults cannot survive harsh winters, females are capable of anticipating seasonal change and producing overwintering diapause (DP) eggs that remain in a state of arrested development over the winter and hatch when favorable conditions return in the spring. While low temperatures can facilitate DP entry under short photoperiods, temperature signals alone are not sufficient to induce DP.

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The Asian tiger mosquito, , is one of the most dangerous invasive species in the world. Females bite mammalian hosts, including humans, to obtain blood for egg development. The ancestral range of likely spanned from India to Japan and this species has since invaded a substantial portion of the globe.

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Animal nervous systems remodel following stress. Although global stress-dependent changes are well documented, contributions of individual neuron remodeling events to animal behavior modification are challenging to study. In response to environmental insults, C.

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Background: A Korean herbal medicine, KOTMIN13, composed of Thunberg, var. , Dunn, and Bge, has been used for anti-allergic and anti-asthmatic treatment in oriental clinics, but its activity has not been investigated.

Materials And Methods: To evaluate the anti-inflammatory activity of KOTMIN13 for study, LPS-stimulated RAW 264.

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Background: The ethanol extract of KOTMIN13, composed of Inula japonica Flowers, Trichosanthes kirilowii Semen, Peucedanum praeruptorum Radix, and Allium macrostemon Bulbs, was investigated for its anti-asthmatic and anti-allergic activities.

Methods: The anti-asthmatic effects of KOTMIN13 were evaluated on ovalbumin (OVA)-induced murine asthma model. Anti-allergic properties of KOTMIN13 in bone-marrow derived mast cells (BMMC) and passive cutaneous anaphylaxis (PCA) in vivo were also examined.

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Article Synopsis
  • - Kisspeptin is crucial for puberty and reproduction, and animals lacking it often face infertility, but recent studies challenge this idea, showing that losing most Kiss1 neurons doesn’t stop reproduction.
  • - The hypothesis is that minimal amounts of kisspeptin could still allow for reproduction, even in animals with drastically reduced Kiss1 expression, suggesting redundancy in its role.
  • - Testing in a specific mouse model revealed that while male mice with severely reduced Kiss1 expression can still reproduce effectively, female mice require higher levels to maintain fertility and normal ovulation.
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