Synopsis of recent research by authors named "In Youb Chang"
- Recent research by In Youb Chang primarily focuses on the mechanisms of cancer biology, particularly in understanding the roles of various proteins and signaling pathways in tumorigenesis and DNA repair processes.
- One of his notable studies explores the relationship between soluble E-cadherin and spheroid formation in colorectal cancer cells, highlighting how cancer stem cells contribute to treatment resistance using 5-fluorouracil (5-FU).
- Chang's findings also reveal the regulatory functions of proteins such as HspBP1, SIAH2, and Ephexin1 in DNA repair, apoptosis, and cell proliferation, indicating potential targets for therapeutic strategies against various cancers, including colorectal and breast cancers.
