Anti-Acne Vulgaris Effects of Pedunculagin from the Leaves of by Anti-Inflammatory Activity and 5α-Reductase Inhibition.

(QM)-a member of the Fagaceae family-has been used as traditional medicine in Korea, China and Mongolia as a treatment for inflammation of oral, genital or anal mucosa and for external inflammation of skin. To treat acne vulgaris (AV), we evaluated the inhibition of inflammatory cytokines (IL-6 and IL-8) of QM leaf extract (QML) and its main compound, pedunculagin (PD) in vitro and 5α-reductase inhibitory activity by western blotting. As results, QML and PD showed potent NO production inhibitory activity compared with the positive control (PC), NG-monomethyl-L-arginine (L-NMMA).

Anti-Inflammatory Effects of Phenolic Compounds Isolated from Fisch. ex Ledeb. on UVB-Irradiated Human Skin Cells.

Fisch. ex Ledeb. (QM) has been used as an oriental traditional medicine to relieve hemorrhoids, fever, and enteritis.

Anti-Obesity Activities of Chikusetsusaponin IVa and L. Seeds.

Obesity, a condition where excess body fat accumulates to the extent, causes a negative effect on health. Previously, we reported the extract of L. (DLL-Ex) inhibited high-fat diet (HFD)-induced increases in body weight and body fat mass and ameliorated increases in body weight.

Anti-skin ageing effects of phenolic compounds from .

(CT) is distributed through in southern regions of South Korea. Six known compounds, including three ellagitannins, one gallotannin, and two flavonoids were isolated from CT. In conclusion, the tannins, especially ellagitannins, and CT extract showed potent anti-oxidative, anti-inflammatory and anti-skin ageing activities.