[Lobectomy performed through a video-assisted mini thoracotomy, as a new technique in our clinical practice].

Unlabelled: In this retrospective study, we present our experiences and results with lobectomy performed through video-assisted mini thoracotomy (VAMT), a technique that we have been using since 2006.

Method And Patients: In the first half of 2006 10 video-assisted lobectomies were performed in our department. There were eight women and two men; the mean age was 61.

Lung cancer as a second primary malignant tumor: prognostic values after surgical resection.

Prognostic values of lung cancers as second primary malignant tumors (LC-as-SPTs) developed after a different type of first primary malignant tumor were analyzed. Forty-three patients underwent surgery for first primary malignant tumors and later for LC-as-SPTs. The most frequent first primary tumors were: 14 laryngo-pharyngeals; 7 lungs; and 5 colons.

Visceral pleural infiltration as a negative prognostic factor in lung metastasis.

The prognostic value of visceral pleural infiltration in lung metastasis was analysed. Fifty-two patients (32 males and 20 females) were operated on for lung metastases. The locations of the primary tumours were as follows: 19 colon, 10 kidneys, 8 melanomas, 3 breast, 3 bladder, 2 uterus, 2 osteosarcomas, 1 testis, and 1 parotid, 1 haemangiopericytoma, 1 thyroid gland and 1 larynx.

The role of microvascularization and growth/adhesion-regulatory lectins in the prognosis of non-small cell lung cancer in stage II.

Objective: To investigate the role of growth/adhesion-regulatory lectins in the prognosis of the stage II non-small cell lung carcinomas (NSCLCs) via quantitative lectinhistochemical examinations and measurement of microvascularization of the tumour.

Methods: In 94 radically operated lung cancer patients, stage II NSCLC was confirmed histologically (T1N1: 6, T2N1: 66, T3N0: 22). Immunohistochemical methods were applied to investigate the galectin-1, galectin-3, CL-16 and hyaluronic-acid-binding capacities of the tumours, and also the expression of galectin-1, -3 and heparin binding lectin.

[Video-assisted, extended thymectomy for the treatment of myasthenia gravis. Our early experiences].

Introduction: Extended thymectomy is the key-point of the surgical treatment of the myasthenia gravis (MG), when the thymus with the surrounding fatty tissue on the neck and in the mediastinum is removed. In this study we present a new surgical technique introduced into our practice in November 2004, and with that the thymectomy is performed with video-thoracoscopic method, without sternotomy.

Patients And Methods: Since November 2004, 6 patients (5 females and 1 male) were operated on for MG.

[Prognostic role of microvascularization in surgically treated lung cancer].

Objective: The aim of our study was the determination of microvascularization and its prognostic significance in lung cancer patients.

Methods: Histological sections were prepared from paraffin-embedded tissues removed from the peripheral part of the tumor of 450 radically operated non-small cell and small cell lung cancer patients. Immunohistochemical staining was performed with antibody against factor VIII-associated antigen.

Prognostic significance of endogenous adhesion/growth-regulatory lectins in lung cancer.

Objective: To determine the expression of endogenous adhesion/growth-regulatory lectins and their binding sites using labeled tissue lectins as well as the binding profile of hyaluronic acid as an approach to define new prognostic markers.

Methods: Sections of paraffin-embedded histological material of 481 lungs from lung tumor patients following radical lung excision processed by a routine immunohistochemical method (avidin-biotin labeling, DAB chromogen). Specific antibodies against galectins-1 and -3 and the heparin-binding lectin were tested.

Prognostic significance of microvascularization in cases of operated lung cancer.

Objective: Measurement of microvascularization and determination of its prognostic significance in cases of lung cancer.

Methods: Section prepared from histological material from 432 radically operated non-small cell lung cancer patients were stained with antibodies against factor VIII-associated antigen. During computer imaging, the absolute and relative parameters of the vascularization were determined, as was the density of tumour cells situated in the vicinity of the vessels.

[Results and alternatives in the surgical treatment of lung cancer].

Objective: The aim of our study was to analyse the results of surgical treatment in lung cancer cases.

Patients And Methods: Between 1990 and 1999, 860 patients were operated on for primary lung cancer. In 775 patients (90.

Lung cancer and its operable brain metastasis: survival rate and staging problems.

Background: We assessed the survival rates regarding different stages of operable lung cancers causing operable brain metastasis in patients with or without cancer-related symptoms. The correlation between survival rates and the disease-free interval between lung surgery and metastasectomy was studied.

Methods: Sixty-five patients were operated on for lung cancer and brain metastases.

Combined off-pump coronary artery by-pass and right upper lobectomy for lung cancer through median sternotomy.

Patients who smoke are at risk of both coronary artery disease and lung cancer, but concomitant lesions of the heart and lung are uncommon. Management of these concomitant lesions is controversial because of the systemic side-effects of a cardiopulmonary by-pass (CPB) and the difficult approach of the lung. An off-pump coronary artery by-pass (OPCAB) can be a successful procedure in the combined treatment of lung cancer and cardiac disease.

[Pancreas resection for lung cancer metastasis].

This case report describes the successful resection of a solitary pancreatic metastasis that developed 21 months following lobectomy of an early pulmonary adenocarcinoma (pT1N0M0). The metastasis caused no complaints. The resected pancreas contained a glucagonoma in addition to the metastasis.

[Prognostic significance of intrapulmonary metastases in cases of surgically treated lung cancer].

Objective: The aim of this retrospective study was to establish the prognosis in lung tumour cases in which resection was followed by synchronous or metachronous intrapulmonary metastasis.

Methods: Between 1990 and 1999, 857 patients were operated on for primary lung cancer. Intrapulmonary metastases were observed in 21 patients.

[The occurrence of bronchioloalveolar lung cancer among our patients].

Introduction: One of the subtypes of pulmonary adenocarcinoma, bronchioloalveolar carcinoma (BAC), is mentioned as the lung cancer of non-smoking women. We have studied the clinical characteristics of BAC and its surgical treatment.

Methods And Patients: Between 1992 and 2001, lung resections for BAC were performed on 101 patients: 55 men and 46 women, average age 59.

[Histological and immunohistochemical structure of pulmonary tuberculotic granulomas in untreated cases and cases treated with antitubercular drugs].

Introduction: The changes occurring in response to antituberculotic treatment and immune defence were studied in human tuberculotic granulomas.

Aims: To compare the possibilities of detection of Mycobacterium tuberculosis with the Ziehl-Neelsen staining technique and with an immunohistochemical method, and to assess the roles of lymphocytes and heat-shock protein 70.

Method: 40 patients who had undergone lung resection (the postoperative histology confirmed tuberculosis) were divided into two equal groups, on the basis of whether they had received antituberculotic treatment preoperatively (group I) or not (group II).

Bronchioloalveolar lung cancer: occurrence, surgical treatment and survival.

Objective: The prevalence of pulmonary adenocarcinoma has risen worldwide. Bronchioloalveolar carcinoma (BAC) was studied with regard to whether it exhibits a similar tendency, and its typical features were analysed.

Methods: Between 1992 and 2001, 278 lung resections were carried out for adenocarcinoma.

Vascular diffusion density and survival of patients with primary lung carcinomas.

Aim: To investigate the clinical significance of tumour vascularisation in operated lung cancer patients.

Materials And Methods: Histological slides obtained from 498 patients with potentially curative operated lung carcinomas in two different institutions of thoracic surgery were immunohistochemically stained with an anti-CD34 antibody and subjected to quantitative image analysis. Syntactic structure analysis measured the absolute and relative features of vessels, including the numerical tumour cells densities relative to their nearest neighbouring vessel.

Development of brain metastasis 5 years before the appearance of the primary lung cancer: "messenger metachronous metastasis".

We report a patient with a brain metastasis that presented 5 years before the primary adenocarcinoma of the lung from which it originated. The metastasis and the primary tumor were removed. To confirm their common origin, we used comparative genomic hybridization.