Modified alginate-chitosan-TiO composites for adsorptive removal of Ni(II) ions from aqueous medium.

In this study, organo-funtionalization of sodium-alginate has been carried out using phenylsemicarbazide as modifier to graft N, O-donor atoms containing functional groups (amino-carbamate moieties) to offer novel support for TiO immobilization. Hybrid composite made of aminocarbamated alginate, carboxymethyl chitosan (CMC) and titanium oxide TiO (MCA-TiO) was prepared for the promising adsorptive remediation of Ni(II). FT-IR, SEM-EDX were employed to characterize MCA-TiO.

A New Pedestrian Crossing Level of Service (PCLOS) Method for Promoting Safe Pedestrian Crossing in Urban Areas.

Crosswalks are critical locations in the urban transport network that need to be designed carefully as pedestrians are directly exposed to vehicular traffic. Although various methods are available to evaluate the level of service (LOS) at pedestrian crossings, pedestrian crossing facilities are frequently ignored in assessing crosswalk conditions. This study attempts to provide a comprehensive framework for evaluating crosswalks based on several essential indicators adopted from different guidelines.

Fabrication of a novel hybrid biocomposite based on amino-thiocarbamate derivative of alginate/carboxymethyl chitosan/TiO for Ni(II) recovery.

A novel hybrid biocomposite based on amino-thiocarbamate derivative of alginate, carboxymethyl chitosan and TiO (TiO/TSC-CMC) was fabricated and characterized using Fourier transform Infrared spectroscopy (FTIR), Scanning electron microscopy (SEM) and Energy dispersive X-ray spectroscopy (EDX). The TiO/TSC-CMC mass ratio (5.0-30.

Amino-carbamate moiety grafted calcium alginate hydrogel beads for effective biosorption of Ag(I) from aqueous solution: Economically-competitive recovery.

In present study, pure and amino-carbamate moiety grafted calcium alginate hydrogel beads (CA, PSC-CA) were prepared for their biosorption performance in the recovery of silver ions. The produced sorbents were characterized using FTIR, SEM, EDX and TGA. FTIR and SEM-EDX confirmed the successful modification and loading of silver ions onto hydrogel beads.

COX7A1 suppresses the viability of human non-small cell lung cancer cells via regulating autophagy.

COX7A1 is a subunit of cytochrome c oxidase, and plays an important role in the super-assembly that integrates peripherally into multi-unit heteromeric complexes in the mitochondrial respiratory chain. In recent years, some researchers have identified that COX7A1 is implicated in human cancer cell metabolism and therapy. In this study, we mainly explored the effect of COX7A1 on the cell viability of lung cancer cells.

Paracrine action of human placental trophoblast cells attenuates cisplatin-induced acute kidney injury.

Aims: The action of cell-based therapy against acute kidney injury (AKI) has been demonstrated by different groups for years. However, which kind of cells hold best therapeutic effect remains unclear. In this study, we mainly explored whether human placental trophoblast cells hold the potential to be applied in AKI therapy.

5‑Azacytidine treatment results in nuclear exclusion of DNA methyltransferase‑1, as well as reduced proliferation and invasion in human cytomegalovirus‑infected glioblastoma cells.

Glioblastoma (GBM) is the most aggressive form of brain tumor in adults, with a devastating outcome. Emerging evidence shows that human cytomegalovirus (HCMV) proteins and nucleic acids are present in GBM tissues. DNA methylation is important for the initiation and progression of cancer and is an established host response against invading nucleic acids.

Isolation and Identification of from Enteric Fever Patients at Different Hospitals of Quetta City.

Background And Objective: Salmonella paratyphi cause enteric fever which is an important public health problem worldwide. In Pakistan incidence is increasing and affect all age groups. Therefore, the present research was designed to study the different microbiological aspects of Salmonella paratyphi.

Integrin α9 gene promoter is hypermethylated and downregulated in nasopharyngeal carcinoma.

Epigenetic silencing of tumor suppressor genes (TSGs) by promoter methylation can be an early event in the multi-step process of carcinogenesis. Human chromosome 3 contains clusters of TSGs involved in many cancer types including nasopharyngeal carcinoma (NPC), the most common cancer in Southern China. Among ten candidate TSGs identified in chromosome 3 using NotI microarray, ITGA9 and WNT7A could be validated.

Detection of nasopharyngeal carcinoma in Morocco (North Africa) using a multiplex methylation-specific PCR biomarker assay.

Background: Silencing of tumor suppressor genes (TSGs) or activation of oncogenes by, e.g., aberrant promoter methylation, may be early events during carcinogenesis.

Development of a multiplex methylation specific PCR suitable for (early) detection of non-small cell lung cancer.

Lung cancer is a worldwide health problem and a leading cause of cancer-related deaths. Silencing of potential tumor suppressor genes (TSGs) by aberrant promoter methylation is an early event in the initiation and development of cancer. Thus, methylated cancer type-specific TSGs in DNA can serve as useful biomarkers for early cancer detection.

Development of a non-invasive method, multiplex methylation specific PCR (MMSP), for early diagnosis of nasopharyngeal carcinoma.

Increasing evidence demonstrated that inactivation of tumor suppressor genes (TSGs) by aberrant promoter methylation is an early event during carcinogenesis. Aiming at developing early diagnostic or prognostic tools for various tumors, we took an EBV-associated tumor, nasopharyngeal carcinoma (NPC), as a model and developed a powerful assay based on "multiplex methylation specific-PCR (MMSP)". The MMSP assay was designed to detect tumor-specific methylation status of several NPC-related genes and was capable of acquiring multiplex information simultaneously through a single PCR reaction with the tiny tumor DNA derived from the direct body fluid close to the primary tumor.