Publications by authors named "Imran Khan-Niazi"

Objectives: This study aimed to elucidate the mechanisms of chiropractic care using resting electroencephalography (EEG), somatosensory evoked potentials (SEPs), clinical health assessments (Fitbit), and Patient-reported Outcomes Measurement Information System (PROMIS-29).

Methods: Seventy-six people with chronic low back pain (mean age ± SD: 45 ± 11 years, 33 female) were randomised into control ( = 38) and chiropractic ( = 38) groups. EEG and SEPs were collected pre and post the first intervention and post 4 weeks of intervention.

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Background: Cardiac rehabilitation programmes, while demonstrating benefits, face challenges in universal adoption, particularly in New Zealand. This study evaluates the long-term impact of cardiac rehabilitation participation and attendance on survival and readmission rates in the Auckland Health District.

Objective: To examine the impact of patient participation in nurse-led lifestyle rehabilitation and physiotherapy exercise rehabilitation on key outcomes, including all-cause mortality, and all-cause, cardiac-specific, and kidney disease readmission rates.

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Article Synopsis
  • - Pain is a major issue for about 70% of chronic pancreatitis patients, but the nature of this pain varies among individuals, complicating treatment approaches.
  • - The INPAIN study will analyze 400 chronic pancreatitis patients and include a control group, using a specialized testing panel over four years to identify pain profiles and predict treatment responses.
  • - This research aims to create a bedside tool that personalizes treatment strategies for chronic pancreatitis pain, potentially leading to better patient outcomes and reduced side effects.
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Background: Non-specific low back pain is a common and costly global issue. Many people with low back pain live for years with ongoing symptom recurrence and disability, making it crucial to find effective prevention strategies. Motivational interviewing (MI) is an evidence-based patient-centred counselling style that helps motivate individuals to change their behaviours.

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  • The study assesses the reliability of measuring ankle dorsiflexor muscle strength and rate of force development (RFD) in individuals who have had a stroke, highlighting the importance for rehabilitation efficacy.
  • Results showed excellent reliability for isometric maximal voluntary contraction (MVC) of the dorsiflexor muscles, while other measures, like TA EMG and RFD, showed good to moderate reliability, questioning their consistency.
  • The conclusion suggests further large-scale studies are needed to better understand the reliability of these measurements, especially concerning rapid force production in stroke patients.
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Despite most episodes of low back pain (LBP) being short-lasting, some transition into persistent long-lasting problems. Hence, the need for a deeper understanding of the physiological mechanisms of this is pertinent. Therefore, the aims of the present study are (1) to map pain-induced changes in brain activity and blood gene expression associated with persistent LBP, and (2) to explore whether these brain and gene expression signatures show promise as predictive biomarkers for the development of persistent LBP.

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Introduction: Mild cognitive impairment (MCI) is a stage between health and dementia, with various symptoms including memory, language, and visuospatial impairment. Chiropractic, a manual therapy that seeks to improve the function of the body and spine, has been shown to affect sensorimotor processing, multimodal sensory processing, and mental processing tasks.

Methods: In this paper, the effect of chiropractic intervention on Electroencephalogram (EEG) signals in patients with mild cognitive impairment was investigated.

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Background: The use of diagnostic imaging in low back pain (LBP) management is often inappropriate, despite recommendations from clinical practice guidelines. There is a limited understanding of factors that influence the imaging clinical decision-making (CDM) process.

Aim: Explore the literature on factors influencing imaging CDM for people with LBP and consider how these findings could be used to reduce inappropriate use of imaging in LBP management.

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Objectives: In this study, we explored the effects of chiropractic spinal adjustments on resting-state electroencephalography (EEG) recordings and early somatosensory evoked potentials (SEPs) in Alzheimer's and Parkinson's disease.

Methods: In this randomized cross-over study, 14 adults with Alzheimer's disease (average age 67 ± 6 years, 2 females:12 males) and 14 adults with Parkinson's disease (average age 62 ± 11 years, 1 female:13 males) participated. The participants underwent chiropractic spinal adjustments and a control (sham) intervention in a randomized order, with a minimum of one week between each intervention.

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Background: Attention deficit hyperactivity disorder (ADHD) is a neurobiological disorder characterized by inattention, hyperactivity, and impulsivity. We hypothesized that chiropractic adjustments could improve these symptoms by enhancing prefrontal cortex function. This pilot study aimed to explore the feasibility and efficacy of 4 weeks of chiropractic adjustment on inattention, hyperactivity, and impulsivity in children with ADHD.

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Mild Cognitive Impairment (MCI) is the primary stage of acute Alzheimer's disease, and early detection is crucial for the person and those around him. It is difficult to recognize since this mild stage does not have clear clinical signs, and its symptoms are between normal aging and severe dementia. Here, we propose a tensor decomposition-based scheme for automatically diagnosing MCI using Electroencephalogram (EEG) signals.

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With the astounding ability to capture a wealth of brain signals, Brain-Computer Interfaces (BCIs) have the potential to revolutionize humans' quality of life [...

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Article Synopsis
  • Deep neural networks (DNNs) outperform traditional methods for myoelectric control (MEC) systems but face delays that hinder real-time applications, necessitating an optimized architecture and tuning of hyperparameters.
  • This study explores effective data segmentation methods—disjoint and overlap—and finds that an overlap segmentation (200 ms segment size and 80% overlap) is more effective, leading to better performance metrics.
  • The research also employs Bayesian optimization to refine DNN hyperparameters, achieving a mean classification error rate of 0.08 across tests, establishing a generalized CNN architecture that shows consistent results across different subjects.
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Increasing evidence suggests that a high-velocity, low-amplitude (HVLA) thrust directed at a dysfunctional vertebral segment in people with subclinical spinal pain alters various neurophysiological measures, including somatosensory evoked potentials (SEPs). We hypothesized that an HVLA thrust applied to a clinician chosen vertebral segment based on clinical indicators of vertebral dysfunction, in short, segment considered as "relevant" would significantly reduce the N30 amplitude compared to an HVLA thrust applied to a predetermined vertebral segment not based on clinical indicators of vertebral dysfunction or segment considered as "non-relevant". In this double-blinded, active-controlled, parallel-design study, 96 adults with recurrent mild neck pain, ache, or stiffness were randomly allocated to receiving a single thrust directed at either a segment considered as "relevant" or a segment considered as "non-relevant" in their upper cervical spine.

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Smartphone applications (apps) that utilize embedded inertial sensors have the potential to provide valid and reliable estimations of different balance and gait parameters in older adults with mild balance impairment. This study aimed to assess the reliability, validity, and sensitivity of the Gait&Balance smartphone application (G&B App) for measuring gait and balance in a sample of middle- to older-aged adults with mild balance impairment in Pakistan. Community-dwelling adults over 50 years of age (N = 83, 50 female, range 50-75 years) with a Berg Balance Scale (BBS) score between 46/56 and 54/56 were included in the study.

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Smartphone accelerometry has potential to provide clinicians with specialized gait analysis not available in most clinical settings. The Gait&Balance Application (G&B App) uses smartphone accelerometry to assess spatiotemporal gait parameters under two conditions: walking looking straight ahead and walking with horizontal head turns. This study investigated the validity of G&B App gait parameters compared with the GAITRite® pressure-sensitive walkway.

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Movement-related cortical potentials (MRCPs) have been used extensively in the literature to develop rehabilitation interventions for people with neurological conditions. In this pilot study, we recorded and extracted MRCPs using a water-based cap to determine whether water-based caps are effective. Five participants took part in the study, where their EEG was recorded during single-joint (dorsiflexion) and multiple-joint (sit-to-stand) lower limb movements.

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Background: Rehabilitation technologies for people with stroke are rapidly evolving. These technologies have the potential to support higher volumes of rehabilitation to improve outcomes for people with stroke. Despite growing evidence of their efficacy, there is a lack of uptake and sustained use in stroke rehabilitation and a call for user-centered design approaches during technology design and development.

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Dehydration is a common problem among older adults. It can seriously affect their health and wellbeing and sometimes leads to death, given the diminution of thirst sensation as we age. It is, therefore, essential to keep older adults properly hydrated by monitoring their fluid intake and estimating how much they drink.

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Introduction Most New Zealanders experience low back pain (LBP) at least once throughout their lifetime and many seek help from the large range of health providers in primary care. Accident Compensation Corporation (ACC) funds a significant proportion of those claims, but which services are they funding and what are the costs? Method This was a retrospective audit and descriptive analysis of ACC-funded, non-public hospital healthcare service use by people with LBP in New Zealand (NZ). Outcome measures were the healthcare services accessed by people with ACC-funded LBP,the claims (all occurrences for a service that has generated a payment/year), single contact (with a service), and costs (NZ$) for services between 2009 and 2020.

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Introduction: The EMG filling factor is an index to quantify the degree to which an EMG signal has been filled. Here, we tested the validity of such index to analyse the EMG filling process as contraction force was slowly increased.

Methods: Surface EMG signals were recorded from the quadriceps muscles of healthy subjects as force was gradually increased from 0 to 40% MVC.

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Non-specific low back pain (NSLBP) is a significant and pervasive public health issue in contemporary society. Despite the widespread prevalence of NSLBP, our understanding of its underlying causes, as well as our capacity to provide effective treatments, remains limited due to the high diversity in the population that does not respond to generic treatments. Clustering the NSLBP population based on shared characteristics offers a potential solution for developing personalized interventions.

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Objective: Noisy galvanic vestibular stimulation (nGVS) has been used to facilitate vestibular function and improve gait and balance in people with poor postural control. The aim of this scoping review is to collate, summarize and report on the nGVS parameters that have been used to augment postural control.

Method: A systematic scoping review was conducted up to December 2022.

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This study examined the incidence and severity of adverse events (AEs) of patients receiving chiropractic spinal manipulative therapy (SMT), with the hypothesis that < 1 per 100,000 SMT sessions results in a grade ≥ 3 (severe) AE. A secondary objective was to examine independent predictors of grade ≥ 3 AEs. We identified patients with SMT-related AEs from January 2017 through August 2022 across 30 chiropractic clinics in Hong Kong.

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Article Synopsis
  • Certain blood biomarkers like BDNF, IGF-II, and GDNF play a role in neural protection and recovery, but their response to chiropractic care in stroke patients hasn't been studied extensively.
  • A trial comparing chiropractic care combined with physical therapy to sham chiropractic with physical therapy evaluated these biomarkers in 63 adults with chronic stroke over eight weeks.
  • Results showed decreases in BDNF and IGF-II and an increase in GDNF in both groups, but no significant differences between the two treatment groups, indicating a need for more research on how chiropractic adjustments affect these biomarkers.
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