Publications by authors named "Imran J Khan"

Purpose: To report on the diagnostic outcomes and safety of full diagnostic vitrectomy (FDV) with surgical posterior vitreous detachment induction for diagnosing vitritis of uncertain etiology.

Methods: Forty-nine patients underwent primary FDV using the cassette washings for histopathological analysis. In addition, an undiluted core vitreous sample was obtained for microbial analysis in suspected infective cases.

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A 19-year-old woman presented with a 4-week history of headache, ataxia, vertigo, confusion, intermittent blurred vision in the right eye and intermittent hearing loss. MRI revealed white matter lesions and 'pepper pot' lesions of the corpus callosum. The cerebrospinal fluid had raised protein and lymphocytes.

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Purpose: Quantifying the extent of conjunctival fibrosis for documentation of progression in conjunctival scarring disease is a clinical challenge. Measurement of forniceal foreshortening facilitates monitoring of these disorders. This study aims (1) to define the limits of the normal human conjunctival fornices and how these alter with age and (2) to provide normative data for upper and lower fornix depths (FDs) and fornix intercanthal distance (FICD) within a healthy South Asian, racially distinct population.

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Purpose: To report a case of macular hole-related retinal detachment in a hyperopic patient and a sequential surgical approach to repair.

Methods: Case report.

Patients: A single patient with acute macular hole-related retinal detachment.

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Aims: Severe ocular inflammation is a blinding ophthalmological emergency. This study evaluates the efficacy and patient tolerance of a validated regime of pulsed intravenous cyclophosphamide and methylprednisolone ('PICM protocol') for these patients.

Methods: 26 patients with severe inflammatory eye disease (43 eyes: 22 uveitis, 21 scleritis/sclerokeratitis; median age 52 years (IQR 40.

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The purpose of this article was to describe a patient with dome-shaped macula in the setting of mild myopic anisometropia and to speculate regarding the role of this feature as a compensatory mechanism in ocular development. The clinical records of a 49-year-old woman with this condition were reviewed. Spectral-domain optical coherence tomographic images revealed evidence of a dome-shaped macula.

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Purpose: To report optical coherence tomography and microperimetry findings in acute macular neuroretinopathy.

Methods: Case report.

Patients: A single patient with acute macular neuroretinopathy.

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Purpose: To report the intraoperative experience and early postoperative results of implantation of an intraocular lens (IOL) developed specifically for myopic eyes.

Setting: Wolverhampton Eye Infirmary, Wolverhampton, United Kingdom.

Methods: This retrospective study evaluated consecutive highly myopic eyes having implantation of a Bigbag IOL from November 2003 to December 2007.

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An 84-year-old white female with nonprogressive conjunctival scarring developed infectious crystalline keratopathy (ICK) recalcitrant to topical therapy. After determination of the causative organism's antibiotic sensitivities, superficial keratectomy was performed with intrastromal corneal infiltration of cefuroxime into the affected cornea. Postoperatively, the ICK resolved completely, leading to an improvement in visual acuity and a reduction in ocular irritation.

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Objective: To determine the incidence of pneumonia and severe pneumonia among children living at high altitudes in Pakistan.

Methods: A longitudinal cohort study was conducted in which 99 female government health workers in Punial and Ishkoman valleys (Ghizer district, Northern Areas of Pakistan) enrolled children at home, conducted home visits every 2 weeks and actively referred sick children to 15 health centres. Health centre staff used Integrated Management of Childhood Illness criteria to screen all sick children aged 2-35 months and identify those with pneumonia or severe pneumonia.

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