Publications by authors named "Immanuel David Charles"

Synthetic molecular sensors are crucial for real-time monitoring in biological systems and biotechnological applications, where detecting targets amidst potential interferents is essential. This task is particularly challenging in competitive environments that lacking chemically reactive functional groups, common in agricultural, biological, and environmental contexts. Consequently, scientific efforts have focused on developing sensitive and rapid analytical techniques, with fluorescent sensors emerging as prominent tools.

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Buprofezin (BUP) is an insect growth regulator widely used in agriculture to control hemipteran pests, particularly the melon aphid, Aphis gossypii, due to its efficiency and low toxicity. Although approved by the Chinese government, its maximum residue limit (MRL) in food is strictly regulated, and conventional techniques for detecting BUP have several limitations. Our study reports successful BUP detection using a supramolecular fluorescent probe DP@ALB, constructed with chalcone-based fluorescent dye DP and albumin as the host.

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A novel ratiometric analytical method based on a quantum dot (QD)-integrated supramolecular sensing system successfully achieves the portable on-site detection of nitroxynil.

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Background: Detecting and neutralizing Pd ions are a significant challenge due to their cytotoxicity, even at low concentrations. To address this issue, various chemosensors have been designed for advanced detection systems, offering simplicity and the potential to differentiate signals from different analytes. Nonetheless, these chemosensors often suffer from limited emission response and complex synthesis procedures.

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Three simple dipodal artificial acyclic symmetric receptors, , , and , driven by positional isomerism based on xylelene scaffolds were designed, synthesized, and characterized by H NMR, C NMR, and mass spectroscopy techniques. Probes , , and demonstrated selective detection of Ag metal ions and amino acid l-histidine in a DMSO-HO solution (1:1 v/v, HEPES 50 mM, pH = 7.4).

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Unlabelled: A novel thiazole phenol conjugate, 2-aminothiazolesalicylaldehyde (receptor1) was designed and synthesized for the first time through a single step process via Schiff base condensation reaction. The formation of receptor1 was confirmed by FTIR, C NMR, and H NMR. The IR spectra confirmed the presence of the aldimine formation.

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A quinoline-naphthalene duo-based Schiff base probe (R) was synthesized and characterized by the usual spectroscopic and single-crystal X-ray crystallographic techniques. Probe R detects Al and HSO ions via the fluorescent turn-on approach by dual pathways i.e.

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The thiazole based Schiff base 2-hydroxy-1-naphthaldehyde-2-amino thiazole (receptor1) was synthesized through a single step process and characterized by spectroscopic and analytical techniques. The cation detecting ability of the receptor1 was explored by fluorescent spectroscopic methods. The receptor1 has recognized Al ions by a turn-on process over a panel of other potentially competing metal ions.

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Article Synopsis
  • A novel dimeric Schiff base probe has been developed for detecting aluminum (Al) and iron (Fe) ions, showing "turn-on" fluorescent and colorimetric responses in a specific solvent mixture.
  • The probe forms a 1:1 complex with the metal ions and operates based on inhibiting photoinduced electron transfer, enabling high sensitivity with detection limits in the nanomolar range.
  • Additional applications of the probe include electrochemical sensing, antimicrobial activity, molecular logic functions, and measuring trace levels of Al and Fe in real water samples.
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