Publications by authors named "Imen Helal"

Introduction: Inflammatory myofibroblastic tumour (IMT) is a rare mesenchymal neoplasm with intermediate biological behavior. Splenic IMT, first described in 1980, is an exceptionally uncommon presentation, with approximately 120 cases reported in the literature by 2021.

Case Presentation: A 52-year-old female presented to the gastroenterology department with complaints of left hypochondrial pain.

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Introduction And Importance: More needs to be understood concerning the natural progression and visual attributes of intracholecystic papillary neoplasm. Its longevity, especially the rate at which it transitions from benign to malignant growths, remains ambiguous. Consequently, it is imperative to elucidate the intrinsic progression of this precancerous lesion in the gallbladder.

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Introduction: Focal acantholytic dyskeratosis is a distinctive histological pattern first described by Ackerman in 1972, consisting of focal suprabasal clefts in the epidermis and dyskeratotic cells at all levels of the epidermis with hyperkeratosis and parakeratosis. The first case of subungual acantholytic dyskeratosis acanthoma (ADA) was reported in 1990. This subungual variant is a very rare entity.

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Introduction: Lichen planus pigmentosus (LPP) is an acquired pigmentary disorder affecting the dark-skinned population. There is a wide range of differentials, with substantial clinicopathological overlap. Dermoscopy may contribute to the better characterization of this dermatosis.

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Background: Solitary fibrous tumors (SFT) are ubiquitous mesenchymal neoplasms of intermediate malignant potential. SFTs of the head and neck are rare, representing less than 0.1% of all SFTs.

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Article Synopsis
  • * A case study of a 54-year-old woman with chronic left upper quadrant pain led to the discovery of a 3.9 cm non-vascular splenic mass, confirmed as cystic lymphangioma through imaging and requiring laparoscopic splenectomy for symptomatic relief.
  • * Though rare in adults, splenic cystic lymphangiomas can necessitate surgery if symptomatic, with imaging being crucial for diagnosis, and laparoscopic splenectomy being the preferred treatment due to its effectiveness and safety.
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  • A patient experienced abdominal pain, fever, bleeding, and a pelvic mass, initially misdiagnosed as a pelvic abscess.
  • After dilation and curettage, pathology confirmed a placental site trophoblastic tumor, leading to an abdominal hysterectomy.
  • Four years post-surgery, the patient remains disease-free, highlighting the need to consider gestational trophoblastic diseases in cases of abnormal uterine bleeding after pregnancy complications.
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Psammocarcinoma is an uncommon subtype of low-grade serous carcinoma. It is characterized by the presence of extensive psammoma bodies and can have either an ovarian or peritoneal origin. To our knowledge fewer than 30 cases of primary peritoneal psammocarcinoma (PPP) have been reported in the English literature.

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  • Spontaneous splenic rupture (SSR) is a rare and serious condition that can occur in both unhealthy and seemingly healthy spleens, often linked to various underlying diseases and requiring urgent medical attention.
  • A case of a 32-year-old male with severe abdominal pain led to a diagnosis of SSR after imaging showed significant internal bleeding, resulting in a splenectomy when conservative treatment failed.
  • Effective management and timely diagnosis through imaging like CT are crucial due to the non-specific symptoms of SSR, which can be confused with other conditions; ongoing research is needed to better understand its causes and risk factors.
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  • Hemangiomas of the small intestine, though rare, can cause serious issues like intussusception, especially in young people, making diagnosis before surgery quite difficult.!* -
  • A case involving a 3-month-old girl highlighted the severity of this condition, as she presented with symptoms of abdominal pain and bleeding, ultimately requiring surgical resection to remove the affected portion of the intestine.!* -
  • Post-surgery, the patient had no complications, indicating that while rare, early recognition and surgical intervention for hemangiomas could lead to positive outcomes, despite the challenges in diagnosis provided typical methods.!*
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Introduction And Importance: Large cell neuroendocrine carcinomas of the colon (LCNECC) are exceptionally rare, comprising only 0.2 % of all colonic carcinomas. Their diagnosis poses a significant challenge due to their propensity to mimic colonic adenocarcinomas.

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Sino-nasal respiratory epithelial adenomatoid hamartomas (REAHs) are rare entity. They are benign tumors with excellent results after complete excision. We report a case of a 57-year-old male with a history of endoscopic surgery for right nasal polyps 20 years ago.

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  • Thyroid carcinoma (TC) represents a small percentage of total cancers worldwide, with its incidence increasing, but there are no significant studies on it in Tunisia.* -
  • A study at a Tunisian health care institute analyzed 192 TC cases over four years, finding a majority of patients were female (83.8%), with papillary thyroid carcinoma being the most common type.* -
  • The results indicated early-stage diagnoses, indicating effective management, but also highlighted the impact of the COVID-19 pandemic on TC treatment, suggesting further research is needed for a comprehensive understanding of TC in Tunisia.*
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Sarcoidosis and the overlap syndrome of autoimmune hepatitis and primary biliary cholangitis (PBC) share common clinical, biological, and histological features. The simultaneous occurrence of these diseases have been reported in few cases and suggests that a common pathway which may contribute to granuloma formation in both conditions. We report the cases of two female patients having an association of sarcoidosis and inflammatory liver diseases.

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In the realm of cancer research, specifically focusing on colorectal carcinomas (CRCs), a novel diagnostic test referred to as 'Immunoscore' (IS) has emerged. This test relies on assessing the density of tumour-infiltrating lymphocytes, specifically CD3 and CD8, in both the centre of the tumour (CT) and its invasive margin (IM). IS holds promise as a potential prognostic factor.

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Introduction And Importance: Locally advanced jejunal stromal tumors stand as a captivating and relatively rare entity, garnering attention for several reasons. Their inaccessible location by conventional endoscopy poses a diagnostic challenge. Further, treatment decisions necessitate a multidisciplinary approach, compounded by the absence of high-level evidence studies.

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Purpose: To describe clinical features and the course of a case of non-necrotizing herpetic retinitis secondary to Varicella zoster virus (VZV).

Materiel And Methods: A single case report documented with multimodal imaging.

Results: A 52-year-old female patient with a past medical history of diabetes mellitus who presented with painful red right eye (OD).

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Pelvic leiomyoma in male patients is a very rare occurrence and its association with prostate cancer is a unique clinical situation. This study reports a new case of a 9 cm pelvic Leiomyoma associated with intermediate-risk localized prostate cancer in a 68-year-old patient. The leiomyoma was discovered fortuitously after an MRI was performed in the context of prostate cancer work-up.

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Immunoscore, based on the evaluation of CD3+ and CD8+ densities in the center of the tumor and its invasive margin, is currently considered as a potential prognostic factor, particularly in colorectal carcinomas. In the current study, we aimed to assess the prognostic value of immunoscore in colorectal cancer stage I to IV, through a survival study. It was a descriptive and retrospective study involving 104 cases of colorectal cancer.

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Necrotizing fasciitis is a dangerous and rapidly spreading infection of soft tissue involving skin, subcutaneous tissue and fascia; muscles can be concerned but often omitted. It's considered as emergency due to its fulminant nature. The necrotizing fasciitis of the breast is exceptional.

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Several hundred cases of placental hemangiomas have been reported in the literature. However, the umbilical cord is extremely uncommon as a site of occurrence. We present a case of postnatal discovery of giant hemangioma of the umbilical cord (HUM) in a Coronavirus Disease 2019 (COVID 19) positive mother.

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