Aneurysmal rupture in microscopic polyangiitis: a case-based review.

Microscopic polyangiitis (MPA) affects small and medium vessel, which sometimes leads to arterial aneurysms. In English database, only 15 reports refer to ruptured aneurysms in MPA. We experienced a fatal case with MPA who developed multiple visceral aneurysms, resulting in rupture of the hepatic aneurysm.

Corrugator Muscle Activity Associated with Pressure Pain in Adults with Neck/Shoulder Pain.

No studies have reported corrugator muscle activity associated with pain in people with pain. This study aimed to develop an objective pain assessment method using corrugator muscle activity with pressure pain stimulation to the skeletal muscle. Participants were 20 adults (a mean ± SD age of 22.

AAV-based gene therapy ameliorated CNS-specific GPI defect in mouse models.

Thirty genes are involved in the biosynthesis and modification of glycosylphosphatidylinositol (GPI)-anchored proteins, and defects in these genes cause inherited GPI deficiency (IGD). is X-linked and involved in the first step of GPI biosynthesis, and only males are affected by variations in this gene. The main symptoms of IGD are neurological abnormalities, such as developmental delay and seizures.

[Resection of Chest Wall Metastasis from Rectal Mucinous Carcinoma-A Case Report].

An 81-year-old woman with rectal mucinous carcinoma underwent a laparoscopic low anterior resection in February 2019, followed by chemotherapy using XELOX plus Bev. The adjuvant chemotherapy was discontinued due to interstitial pneumonia. During a follow-up consultation 2 years later, chest computed tomography(CT)imaging revealed a nodule in her right lung(S9).

Tranexamic acid administration for the prevention of periprosthetic joint infection and surgical site infection: a systematic review and meta-analysis.

Introduction: Tranexamic acid (TXA) has been widely utilized to reduce blood loss and allogeneic transfusions in patients who undergo lower limb arthroplasty. In recent years, there have been several articles reporting the incidence of periprosthetic joint infection (PJI) as a primary outcome of TXA administration, but no meta-analysis has been conducted to date. The present systematic review and meta-analysis evaluated the efficacy of TXA administration in preventing PJI and surgical site infection (SSI).

A case report of a collision tumor composed of pancreatic ductal adenocarcinoma and peri-pancreatic mucosa-associated lymphoid tissue lymphoma.

Background: Collision tumors are composed of two distinct tumor components. Collision tumors composed of pancreatic ductal adenocarcinoma and malignant lymphoma occurring in the pancreas have not been previously described in the scientific literature. In this case report, we describe a unique patient with a collision tumor composed of pancreatic ductal adenocarcinoma and peri-pancreatic mucosa-associated lymphoid tissue (MALT) lymphoma occurring in the pancreas.

[A Case of Laparoscopic Total Gastrectomy for Juvenile Polyposis of Stomach with Synchronous Multiple Intramucosal Carcinomas].

The patient was a 57-year-old woman. She was referred to our hospital because severe anemia. Upper gastrointestinal endoscopy revealed polyposis throughout the stomach and lobulated polyps in cardia, greater curve of middle body of the stomach, and angulus.

Evaluation of generalization ability for deep learning-based auto-segmentation accuracy in limited field of view CBCT of male pelvic region.

Purpose: The aim of this study was to evaluate generalization ability of segmentation accuracy for limited FOV CBCT in the male pelvic region using a full-image CNN. Auto-segmentation accuracy was evaluated using various datasets with different intensity distributions and FOV sizes.

Methods: A total of 171 CBCT datasets from patients with prostate cancer were enrolled.

Computed Tomography slice interpolation in the longitudinal direction based on deep learning techniques: To reduce slice thickness or slice increment without dose increase.

Large slice thickness or slice increment causes information insufficiency of Computed Tomography (CT) data in the longitudinal direction, which degrades the quality of CT-based diagnosis. Traditional approaches such as high-resolution computed tomography (HRCT) and linear interpolation can solve this problem. However, HRCT suffers from dose increase, and linear interpolation causes artifacts.

Application of noninvasive positive pressure ventilation to respiratory complications of severe tetanus: a case report.

Respiratory failure because of muscle spasms is a major sequela of tetanus. Spasms can be controlled with sedation and adjunctive treatment, albeit at the expense of respiratory drive and weakness. Invasive ventilation under deep sedation with intensive care unit admission is the best practice.

Improvement of Image Quality of Cone-beam CT Images by Three-dimensional Generative Adversarial Network.

Artifacts and defects in Cone-beam Computed Tomography (CBCT) images are a problem in radiotherapy and surgical procedures. Unsupervised learning-based image translation techniques have been studied to improve the image quality of head and neck CBCT images, but there have been few studies on improving the image quality of abdominal CBCT images, which are strongly affected by organ deformation due to posture and breathing. In this study, we propose a method for improving the image quality of abdominal CBCT images by translating the numerical values to the values of corresponding paired CT images using an unsupervised CycleGAN framework.

Meticulous closure of collateral vessels in the perihilar mediastinal pleura to control intraoperative bleeding during lung transplantation for pulmonary hypertension.

Background: Massive blood transfusion compensating hemorrhage during lung transplantation (LT) results in primary graft dysfunction (PGD) and worse outcomes after LT. Collateral vessels in the perihilar mediastinal pleura could be the source of hemorrhage during LT in patients with pulmonary hypertension (PH). The purpose of this study was to examine the effect of closure with hemoclips of the vessels in the perihilar mediastinal pleura on the risk of intraoperative hemorrhage and outcomes after LT in patients with PH.

Butyrylcholinesterase level as an independent prognostic factor for overall survival in patients on maintenance hemodialysis: a single-center retrospective study.

Background: We investigated whether butyrylcholinesterase (BChE) was independently related to the overall survival (OS) of patients on maintenance hemodialysis (MHD).

Methods: Baseline information, serum BChE level, and other laboratory data were collected from 295 patients on MHD in a single HD hospital in 2018. We retrospectively investigated the mortality of these patients after 38 months.

Primary omental torsion diagnosed and treated laparoscopically: a case report.

Omental torsion, a rare cause of acute abdomen in children and adults, is difficult to correctly diagnose before surgery because it mimics the common causes of acute surgical abdomen. We present a case of greater omental torsion that was diagnosed by laparoscopy. A 37-year-old man presented with right lower abdominal pain and was suspected to have appendicitis.

Geometric and dosimetric impact of 3D generative adversarial network-based metal artifact reduction algorithm on VMAT and IMPT for the head and neck region.

Background: We investigated the geometric and dosimetric impact of three-dimensional (3D) generative adversarial network (GAN)-based metal artifact reduction (MAR) algorithms on volumetric-modulated arc therapy (VMAT) and intensity-modulated proton therapy (IMPT) for the head and neck region, based on artifact-free computed tomography (CT) volumes with dental fillings.

Methods: Thirteen metal-free CT volumes of the head and neck regions were obtained from The Cancer Imaging Archive. To simulate metal artifacts on CT volumes, we defined 3D regions of the teeth for pseudo-dental fillings from the metal-free CT volumes.

Intermediate snapshots of a 116-nuclear metallosupramolecular cage-of-cage in a homogeneous single-crystal-to-single-crystal transformation.

Soaking crystals of an AuI72CdII40NaI4 cage-of-cage in aqueous Co(NO3)2 afforded an analogous AuI72CoII44 cage-of-cage, accompanied by the exchange of NaI and CdII by CoII with retention of the single crystallinity. The homogeneous progress of the transformation led to the direct observation of intermediate species by single-crystal X-ray crystallography.

Two-step seismic noise reduction caused by COVID-19 induced reduction in social activity in metropolitan Tokyo, Japan.

The COVID-19 pandemic that started at the end of 2019 forced populations around the world to reduce social and economic activities; it is believed that this can prevent the spread of the disease. In this paper, we report an analysis of the seismic noise during such an induced social activity reduction in the Tokyo metropolitan area, Japan. Using seismic data obtained from 18 stations in the Metropolitan Seismic Observation Network (MeSO-net), a two-step seismic noise reduction was observed during the timeline of COVID-19 in Tokyo.

Comparison of safety between high and low doses of sulbactam/ampicillin: A retrospective observational study in Japanese patients with pneumonia.

Although 12 g/day sulbactam/ampicillin (SBT/ABPC) is approved in Japan, differences in the frequency of adverse effects induced by conventional (≤6 g/day) and high (≥9 g/day) doses remain unclear. We performed a retrospective observational study on SBT/ABPC-treated hospitalized adult patients with pneumonia from October 2015 to January 2018 to compare the safety between high and low doses. Patients were divided into high-dose (≥9 g/day, n = 200) and low-dose (≤6 g/day, n = 246) groups.

Pre-dialysis serum creatinine as an independent predictor of responsiveness to zinc supplementation among patients on hemodialysis.

Background: To investigate whether pre-dialysis level of serum creatinine (SCre) could indicate the responsiveness to zinc supplementation of patients on maintenance hemodialysis (MHD).

Methods: We retrospectively reviewed the results of our previous randomized study of 91 patients who had been on MHD and received zinc supplementation with either zinc acetate hydrate (ZAH; zinc, 50 mg/day) or polaprezinc (PPZ; zinc, 34 mg/day). A late response to zinc supplementation was defined as a serum zinc level of < 80 μg/dL three months after the study began.

A 116-Nuclear Metallosupramolecular Cage-of-Cage Showing Multistep Single-Crystal-to-Single-Crystal Transformation.

Here a unique single-crystal-to-single-crystal (SCSC) transformation of a 116-nuclear Au Cd Na cage-of-cage (2 ) is reported, which was created from a trigold(I) metalloligand with d-penicillamine by way of a 9-nuclear Au Cd cage (1). Cage-of-cage 2 is composed of 12 cages of 1 that are linked by 4 Cd and 4 Na ions, with its surface being covered by 12 NO ions to form a discrete, spherical molecule with a diameter ca. 4.

Comparison of zinc acetate hydrate and polaprezinc for zinc deficiency in patients on maintenance hemodialysis: A single-center, open-label, prospective randomized study.

The efficacy and safety of zinc acetate hydrate (ZAH) for zinc supplementation in patients on maintenance hemodialysis (MHD) remains unknown. In this prospective, single-center, open-label, parallel-group trial for MHD patients with serum zinc level <70 μg/dL, we compared ZAH (zinc; 50 mg/day) and polaprezinc (PPZ; zinc; 34 mg/day) beyond 6-month administration in a 1:1 randomization manner. The ZAH and PPZ groups had 44 and 47 patients, respectively.