The Association of Selective Serotonin Reuptake Inhibitors with Delirium in Post-Operative Adults: A Secondary Analysis of a Post-Operative Dataset with Daily Severity of Illness Adjustment.

Background: Postoperative delirium is a prevalent condition associated with increased mortality, difficulties with physical recovery from surgery and decreased long-term cognitive function, especially in older adults. Currently, there are no direct medical treatments for delirium. We recently found an association between SSRI administration and reduced delirium in a critically ill medical population.