Colorectal cancer and microbiota: systematic review.

Introduction: The gut microbiome maintains the mucus membrane barrier's integrity, and it is modulated by the host's immune system.

Aim: To detect the effect of microbiota modulation using probiotics, prebiotics, symbiotics, and natural changes on colorectal cancers (CRCs).

Methods: A PubMed search was conducted to retrieve the original and articles published in English language from 2010 until 2021 containing the following keywords: 1) CRCs, 2) CRCs treatment (i.