Association Between rs7574865 Polymorphism and Rheumatoid Arthritis: Debate Unresolved.

Background: rs7574865 polymorphism has been evidently associated with susceptibility to Rheumatoid Arthritis (RA) in European and Eastern Asian populations, whereas studies in other countries reported otherwise.

Objective: We investigated the distribution of rs7574865 polymorphism in a group of Syrian RA patients.

Methods: Eighty-one RA patients and forty healthy controls were enrolled and rs7574865 was genotyped by direct sequencing.