Publications by authors named "Iman Shaban Osheba"
Article Synopsis
- The study investigates the link between the EGF (rs4444903) gene polymorphism and the risk of cholangiocarcinoma (CCA) in Egyptian patients, suggesting that specific genotypes (GG and AG) are associated with higher risks compared to the AA genotype.
- Results indicate that the G allele is significantly connected to increased CCA risk, though its association is less clear in certain genetic models.
- Overall, while there is evidence that the EGF rs4444903 polymorphism may contribute to CCA development, it does not appear to impact the disease's severity.
Aim Of The Study: To evaluate the role of plasma level of von Willebrand factor antigen (vWF-Ag) as a possible predictor for the presence of esophageal varices (EVs) in children with chronic liver diseases (CLDs).
Material And Methods: All patients underwent upper esophagogastroduodenoscopy (EGD) and were categorized as group I (had EVs) and group II (had no EVs). The following patient data were determined: Child-Pugh score (CPS), plasma vWF-Ag, vWF-Ag/thrombocyte ratio (VITRO) score, aspartate transaminase (AST) to platelet ratio index (APRI) score, AST/alanine transaminase (ALT), platelet count/spleen diameter, grading of EVs (small, medium and large) and categorizing the stage of liver fibrosis.