Effects of Treating an Overactive Urinary Bladder in Patients with Multiple Sclerosis.

Objective: The purpose of this study was to evaluate the efficiency of the anticholinergic therapy with oxybutynin and the effects of daily transcutaneous tibial nerve stimulation (TTNS) on the quality of life of patients with an overactive bladder (OAB) and multiple sclerosis (MS).

Patients And Methods: The study was designed as a randomized controlled trial. The patients who suffer from MS underwent urodynamic tests which showed that they had an OAB.

Systemic Inflammatory Response Syndrome in Surgical Patients.

Objective: To determine the incidence of systemic inflammatory response of the organism in surgical patients and its impact on the outcome of treatment.

Methods: A prospective study was conducted on 60 patients undergoing abdominal surgical procedures, between January 2014 and December 2015 in the Surgery Clinic at the University Clinical Center Tuzla. Two groups of thirty were formed by the method of consecutive sampling.

Characteristics and Treatment of Breakthrought Pain (BTcP) in Palliative Care.

Introduction: This research was to follow characteristics of breakthrough pain caused by cancer (BTcP) and other most common sympthoms (ESAS) at patients in advanced stage of cancer disease in palliative care.

Patients And Methods: Prospective study included 433 patients which were treated in Palliative Care Centre in UKC Tuzla, Bosnia and Herzegovina. Group 1 was consisted of 353 patients whose basal cancer pain of intensity 4-7 NRS was treated weak opiates (basal analgetic- fixed combination of tramadol/paracetamol (37.

Changes in activated partial thromboplastin time and international normalised ratio after on-pump and off-pump surgical revascularization of the heart.

Surgical revascularization of the heart (CABG - coronary artery bypass grafting) is one way of treating coronary heart disease. Bleeding is one of the serious and frequent complications of heart surgery and can result in increased mortality and morbidity. Hemostasis disorder may be secondary consequences of surgical bleeding, preoperative anticoagulant therapy, and the use of cardiopulmonary bypass.

Postoperative pain in open vs. laparoscopic cholecystectomy with and without local application of anaesthetic.

Aim: To evaluate the intensity of postoperative pain and benefits of laparoscopic cholecystectomy compared to open cholecystectomy especially after anaesthetic infiltration of surgical incision.

Methods: This prospective cohort study included three groups of 30 patients each, who had undergone surgical treatment by an open procedure, by laparoscopic technique and by laparoscopic technique with local anaesthetic application. All patients were of similar age, sex and ASA risk (American Society of Anaesthesiologists).

Influence of donor age on renal graft function in first seven post transplant days.

Increasing gap between demand and availability of human kidneys for transplantation has forced a re-evaluation of the limits on donor age acceptability. The present study included 74 patients who underwent kidney transplantation in University Clinical Centre Tuzla. In an observational cohort study we assessed impact of donor age on post transplant renal function by analyzing following parameters: 24 hour urine output, creatinine clearance (Cr Cl) and glomerular filtration rate (GFR).

Micophenolat Mofetil versus Azathioprine: effects on renal graft function in early posttransplant period.

All conventional immunosuppressive tree drugs-protocols are based on Cyclosporine; consisting of low doses of Cyclosporine (CsA), Azathioprine (AZA) or Mycophenolate Mofetil (MMF) and Prednisolone. AZA has been used in clinical transplantation for more than 30 years and was the first immunosuppressive agent to achieve widespread use in organ transplantation. MMF was introduced in clinical practice in 1995 after several clinical trials proved that it was more efficient than AZA for prevention of acute rejection episodes.

[Incidence of ARDS in patients with multiple injuries].

Adult respiratory distress syndrome (ARDS) is common complication and cause of death in some patients with polytrauma. Twenty patients with polytrauma were in test group and have had revised trauma score (RTS) nine or less. The aim of this study is to establish an incidence of ARDS, mortality rate and significance of Lung injury score (LIS) in assessment of damage of the lung function.