Proteinuria in relation to age-dependent changes in the plasma and urine concentrations of some electrolytes and hematological indices in Wistar rats.

The study was carried out to determine the influence of proteinuria on plasma and urine concentrations of electrolytes and hematological indices in Wistar rats of different age groups. Eighty Wistar rats of both sexes were used for this study. Groups 1 and 2 each consisted of 8 one month old male and female rats; 3 and 4 had 8 three month old rats; 5 and 6 had 8 six month old rats; 7 and 8 had 8 nine month old rats; 9 and 10 had 8 twelve month old rats.

Neuro-endocrine effects of aqueous extract of (Linn.) leaf in male Wistar rat model of cyclophosphamide-induced reproductive toxicity.

Cyclophosphamide (CP) is a widely used cytotoxic alkylating agent with antitumor and immunosuppressant properties that is associated with various forms of reproductive toxicity. The significance of natural antioxidants of plant origin should be explored, especially in a world with increasing incidence of patients in need of chemotherapy. The neuro-endocrine effects of aqueous extract of (Linn.

Sexually dimorphic proteinuria in Wistar rats: Relevance to clinical models.

The study investigated the relationship between physiological proteinuria and the histomorphometry of the renal corpuscles in apparently healthy Wistar rats of both sexes, belonging to the same age group. This was with a view to appraise any possible connection between potential expression of sexual dimorphism and the histomorphometry of some integral parts of the glomerular filtration barrier. Twenty Wistar rats of both sexes between ages 9 and 10 weeks were used for this study.