Publications by authors named "Imad T Jarjour"

Background: Functional syncope, or psychogenic pseudosyncope, is often under-recognized. We aimed to show that functional syncope may be diagnosed in most pediatric patients by the initial neurological consultation.

Methods: We reviewed the medical records of patients who were evaluated from 2006 to 2022 in clinic for apparent transient loss of consciousness (a-TLOC) and probable functional syncope.

View Article and Find Full Text PDF

Background: Postural tachycardia syndrome (POTS) is associated with complaints of cognitive and emotional difficulties that may contribute to severe functional disability. For high-achieving adolescents, these symptoms can result in decreased participation in school and extracurricular activities. There are very limited data comparing subjective symptom reports to neurocognitive profiles in adolescents presenting with POTS, "brain fog," and cognitive difficulties.

View Article and Find Full Text PDF

Background: Pediatric central nervous system (CNS) phaeohyphomycosis is a rare invasive fungal infection associated with high mortality.

Methods: We describe a child with progressive neurologic symptoms whose ultimate diagnosis was Cladophialophora bantiana -associated CNS phaeohyphomycosis. We discuss her clinical presentation, medical and surgical management and review the current literature.

View Article and Find Full Text PDF

Eosinophilic meningitis can be caused by various etiologies and is reported mostly in tropical climates. The diagnosis is rare in the continental US, presenting challenges for management. Following a case of pediatric eosinophilic meningitis, we reviewed our 11-year experience with this diagnosis at a large US children's hospital.

View Article and Find Full Text PDF

Orthostatic intolerance (OI), having difficulty tolerating an upright posture because of symptoms or signs that abate when returned to supine, is common in pediatrics. For example, ∼40% of people faint during their lives, half of whom faint during adolescence, and the peak age for first faint is 15 years. Because of this, we describe the most common forms of OI in pediatrics and distinguish between chronic and acute OI.

View Article and Find Full Text PDF
Article Synopsis
  • Developmental and epileptic encephalopathy (DEE) combines epilepsy and intellectual disability, often leading to developmental stagnation or decline, with unknown causes in most cases.
  • Researchers conducted whole-genome sequencing on 197 DEE patients and their healthy parents to identify new genetic mutations linked to the condition.
  • They established a molecular diagnosis for 32% of the individuals, finding that de novo point mutations were the primary cause, suggesting a unique genetic profile for DEE compared to intellectual disability without epilepsy.
View Article and Find Full Text PDF

Background: Advances in obstetric and neonatal medical care and assisted reproductive technology have increased the rates of preterm birth, decreased preterm mortality rates, and lowered the limit of viability. However, morbidity in survivors, including neurodevelopmental disabilities, has increased, especially in extremely preterm infants born at ≤25 weeks' gestation. A better understanding of the prevalence and patterns of adverse neurodevelopmental outcomes in extremely preterm infants is important for patient care, counseling of families, and research.

View Article and Find Full Text PDF

Objective: We reported low iron storage in neurally mediated syncope (NMS). While reduced red cell mass indicative of anemia has been reported in POTS, iron indices and hemoglobin (Hb) data were not reported. We investigated whether POTS, like NMS, is associated with low iron storage and anemia.

View Article and Find Full Text PDF

Postural tachycardia syndrome is a chronic condition with frequent symptoms of orthostatic intolerance or sympathetic activation and excessive tachycardia while standing, without significant hypotension. Orthostatic symptoms include dizziness, lightheadedness, blurring of vision, near faints, weakness in legs, poor concentration, nausea, and headaches. Somatic symptoms include fatigue, sleep disorder, widespread pain, abdominal pain, and menstrual irregularities.

View Article and Find Full Text PDF

Objective: To investigate whether neurally mediated syncope (NMS) is associated with low iron storage or serum ferritin (SF).

Study Design: 206 children evaluated between 2000 and 2004 for probable syncope at a tertiary care Pediatric Neurology Clinic were included in a retrospective study. Serum ferritin (SF), iron, total iron binding capacity, and hemoglobin were measured prospectively after initial history taking and physical examination, along with other diagnostic testing.

View Article and Find Full Text PDF

Recurrent epistaxis is a common pediatric problem with uncertain etiology in most cases. We observed frequent complaints, or history of epistaxis in children with migraine. The aim of this study was to determine whether there is an association between epistaxis and migraine in children.

View Article and Find Full Text PDF